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In the production of titanium alloy, the electron beam cold hearth melting (EBCHM) process is commonly used due to its effectiveness and the high quality of the end product. However, its main drawback is the significant loss of elements such as aluminum (Al) due to evaporation under the vacuum environment. Numerical coupled thermal-flow models were here developed to investigate the effects of scanning strategies on Al loss in a titanium alloy during EBCHM. The validation model was successful in comparison with previously published experimental data. The Al mass fraction results at the outlet of the water-cooled hearth were strongly influenced by changes in the applied scanning strategies. The results indicated that the Al mass fraction loss could be reduced by using the full-hearth scanning strategies.
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http://dx.doi.org/10.3390/ma15030820 | DOI Listing |
Eur J Nucl Med Mol Imaging
September 2025
Department of Nuclear Medicine, Changhai Hospital, Naval Medical University, 168 Changhai Road, Yang Pu District, Shanghai, 200433, China.
Purpose: In this retrospective study, whether [Ga]Ga-DOTA-FAPI-04 PET/MR imaging biomarkers can predict the progression-free survival (PFS) and overall survival (OS) of patients with advanced pancreatic cancer was investigated.
Methods: Fifty-one patients who underwent [Ga]Ga-DOTA-FAPI-04 PET/MR scans before first-line chemotherapy were recruited. Imaging biomarkers, including the maximum tumor diameter, minimum apparent diffusion coefficient (ADC), maximum and mean standardized uptake values (SUV and SUV), fibroblast activation protein- (FAP-) positive tumor volume (FTV and W-FTV) and total lesion FAP expression (TLF and W-TLF), were recorded for primary and whole-body tumors.
J Am Chem Soc
September 2025
Department of Chemistry, National Taiwan University, Taipei 106319, Taiwan.
The exclusive formation of artificial multicomponent assemblies remains a significant challenge, in contrast to the well-established organization observed in natural systems, due to intrinsic entropic constraints. To overcome this limitation, recent efforts have been focused on developing precision self-assembly strategies for the rational construction of such architectures. Here, we construct an ideal complementary pair of 2,2':6',2″-terpyridine (tpy)-based ligands by fine-tuning the substituent bulkiness, which enables the quantitative formation of robust nested cages through efficient dynamic heteroleptic complexation with multivalent coordination.
View Article and Find Full Text PDFCancer Med
September 2025
Department of Radiology & Nuclear Medicine, Erasmus MC - University Medical Centre Rotterdam, Rotterdam, the Netherlands.
Aims: This review summarizes the role and future prospects of nuclear medicine in ovarian cancer, focusing on novel radiopharmaceuticals beyond FDG for diagnostic, predictive, and therapeutic applications within a theranostic framework.
Materials And Methods: A narrative literature review was conducted using major databases. Peer-reviewed articles addressing non-FDG radiopharmaceuticals in ovarian cancer were identified and assessed; FDG-based studies were excluded due to the availability of prior comprehensive reviews.
Knee Surg Sports Traumatol Arthrosc
September 2025
Department of Anatomy, Catholic Institute for Applied Anatomy, College of Medicine, The Catholic University of Korea, Seoul, Korea.
Purpose: The purposes of this study were threefold: (1) to evaluate the influence of femoral antecurvature on coronal alignment changes following supracondylar femoral derotational osteotomy (FDO); (2) to investigate the combined effects of derotation angle and osteotomy orientation in relation to femoral antecurvature and (3) to propose a practical strategy for minimising valgus deviation after FDO based sagittal femoral bowing.
Materials And Methods: Sixty-six cadaveric femoral computed tomography (CT) scans were analysed using three-dimensional (3D) simulation. Femurs were classified into three groups based on the degree of antecurvature using the distal diaphyseal angle (DDA).
Analyst
September 2025
Ulm University, Institute of Analytical and Bioanalytical Chemistry, Albert-Einstein-Allee 11, D-89081 Ulm, Germany.
This study aims at the establishment of a universally applicable etching methodology to unveil the nanoscale crystalline structure of the matrix resin in fiber reinforced thermoplastic (FRTP) composites scanning electron microscopy (SEM). The crystalline structure hierarchically consists of crystalline texture, spherulite and lamella. The details of these structures are key parameters to understand the relationship with the mechanical properties of the material for the advancement.
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