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Air pollution has emerged as a major global concern in recent decades as a result of rapid urbanization and industrialization, leading to a variety of adverse health outcomes. This research aims to investigate the influence of exposure to ambient and household particulate matter pollution (PM), and ground-level ozone (O) pollution on respiratory and cardiac mortality in Pakistan. We used grey incidence analysis (GIA) methodology to estimate the degree of proximity among selected variables and rank them based on mortality. Hurwicz's criterion is then adopted for further optimization by prioritizing the selected factors with the greatest influence on respiratory and cardiac mortality. The GIA findings revealed that asthma mortality is considerably impacted by exposure to ambient and household PM concentration while ischemic heart disease (IHD) mortality is potentially influenced by ground-level ozone exposure. Furthermore, results based on Hurwicz's analysis demonstrated that exposure to ambient PM concentration appeared as the most intensified factor of respiratory and cardiac mortality. This corroboration adds to the growing body of research demonstrating that exposure to ambient PM adversely leads to respiratory and cardiac risks, emphasizing the demand for further improvement of air quality in Pakistan. Besides, the suggested methodologies provide a valuable tool and additional practical knowledge for policymakers and decision-makers in drawing rational decisions.
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http://dx.doi.org/10.3389/fpubh.2021.812743 | DOI Listing |
J Hazard Mater
September 2025
Institute of Environment, Florida International University, 3000 NE 151st St., Biscayne Bay Campus, North Miami, FL 33181, USA; Department of Chemistry and Biochemistry. Florida International University, 11200 SW 8th Street, Modesto A. Maidique Campus, Miami, FL 33199, USA. Electronic address: nsoar
Per- and polyfluoroalkyl substances (PFAS) are man-made pollutants widely used in industrial and consumer products, known to pose significant health risks. While their occurrence in water, soil, and food has been extensively studied, limited research has focused on ambient air, particularly in the U.S.
View Article and Find Full Text PDFArch Environ Contam Toxicol
September 2025
Department of Environmental Engineering, Faculty of Engineering and Natural Sciences, Bursa Technical University, Mimar Sinan Mahallesi Mimar Sinan Bulvarı Eflak Caddesi No:177, 16310, Yıldırım, Bursa, Turkey.
This study investigates airborne concentrations of six insecticides widely used on crops grown in agricultural, semi-urban, and rural areas of Bursa Province, Türkiye. Sorbent-impregnated passive air samplers (SIP-PASs), consisting of polyurethane foam (PUF) disks impregnated with XAD-2 resin, were deployed at ten strategically selected sites representing diverse agricultural and demographic profiles within the province. Analytes were quantified using gas chromatography-mass spectrometry (GC-MS) for depuration compounds and liquid chromatography-tandem mass spectrometry (LC-MS/MS) for target insecticides.
View Article and Find Full Text PDFMacromol Biosci
September 2025
Department of Chemistry, Korea Advanced Institute of Science and Technology (KAIST), Daejeon, Republic of Korea.
Conventional gelatin's gel-to-sol transition upon heating restricts its utility in biomedical applications that benefit from a gel state at physiological temperatures such as Pluronic F127 and poly(NIPAAm). Herein, we present "rev-Gelatin", a gelatin engineered with reverse thermo-responsive properties that undergoes a sol-to-gel transition as temperature rises from ambient to body temperature. Inspired by the phase dynamics of common materials like candy and ice cubes, whose surfaces soften or partially melt under warming, facilitating inter-object adhesion- rev-Gelatin leverages this concept to achieve fluidity at room temperature for easy injectability.
View Article and Find Full Text PDFJAMA Neurol
September 2025
Translational Neuropathology Research Laboratory, Department of Pathology and Laboratory Medicine, Perelman School of Medicine at the University of Pennsylvania, Philadelphia.
Importance: Exposure to fine particulate matter air pollution (PM2.5) may increase risk for dementia. It is unknown whether this association is mediated by dementia-related neuropathologic change found at autopsy.
View Article and Find Full Text PDFBiotechniques
September 2025
Woman, Mother + Baby Research Institute, Tufts Medicine, Boston, MA, USA.
MicroRNAs (miRNAs) are considered more stable than mRNA, but the impact of progressive thawing of biological samples after freezing as may happen during shipping delays has not been quantified. To address this, we utilized digital PCR to estimate the absolute concentrations of select miRNAs following progressive thawing of human plasma and maintenance at ambient temperature. Specifically, we quantified let-7b-3p, miR-144-5p, miR-150-5p, miR-517a-3p, miR-524-5p, and miR-1283, which have varying abundance in plasma.
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