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Background: Following open or closed reduction for children with developmental dysplasia of the hip, there remains a significant risk of residual acetabular dysplasia which can compromise the long-term health of the hip joint. The purpose of this study was to use postoperative in-spica magnetic resonance imaging (MRI) data to determine factors predictive of residual acetabular dysplasia at short-term follow-up.
Methods: We retrospectively reviewed 63 hips in 48 patients which underwent closed or open reduction and spica casting for developmental dysplasia of the hip. MRI performed in-spica at ∼3-week follow-up were used to assess 11 validated metrics and 2 subjective factors. Acetabular index (AI) was measured on anteroposterior pelvic radiographs at 2-year postoperative follow-up. Binary logistic regression was then used to identify variables predictive of residual dysplasia, defined as an AI greater than the 90th percentile for age based on historic normative data.
Results: Average age at surgical reduction was 9.3±3.2 months. 58.7% (37/63) of reductions were open. A total of 43 (68.3%) hips demonstrated residual acetabular dysplasia at 2 years postoperatively based on normative values. In those with persistent dysplasia, patients were on average older at the time of reduction (10.0 mo±3.2 vs. 8.0 mo±2.8, P=0.010) and more likely female (88.4% vs. 60.0%, P=0.010). Patients with residual dysplasia were more likely to have mild subluxation on postoperative MRI (40.0% vs. 10.5%, P=0.022). Hips with a cartilaginous acetabular index (CAI) of >23 degrees were 7.6 times more likely to develop residual dysplasia. Type of reduction (ie, closed vs. open) did not appear to influence the rate of residual dysplasia (P=0.682).
Conclusion: In this series, the rate of residual dysplasia after surgical reduction was higher than most previous reports, with no appreciable difference between closed and open reductions. Older age, female sex, and a higher CAI were associated with a greater risk of persistent radiographic dysplasia. In particular, hips with a CAI >23 degrees were 7.6 times more likely to be dysplastic at 2-year follow-up.
Level Of Evidence: Level III.
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http://dx.doi.org/10.1097/BPO.0000000000002062 | DOI Listing |
J Am Acad Orthop Surg
September 2025
From the Department of Orthopedic Surgery, Hospital for Special Surgery, New York, NY (Neitzke, O'Donnell, Buchalter, Chandi, Westrich, and Gausden), the Department of Orthopedic Surgery, University of Wisconsin-Madison, Madison, WI (O'Donnell), and Somers Orthopaedic Surgery & Sports Medicine Group
Introduction: Developmental dysplasia of the hip (DDH) poses challenges for component positioning during total hip arthroplasty (THA) secondary to abnormal bone morphology, soft-tissue contractures, and hip center migration. The objective of this study was to evaluate the radiographic and clinical outcomes of THA for DDH performed with robotic assistance versus manual (M) technique.
Methods: A retrospective review identified 115 patients with Crowe II to IV dysplasia undergoing primary THA at a single institution from 2016 to 2022.
Urology
September 2025
Oregon Health & Science University, Division of Plastic & Reconstructive Surgery, Portland, OR, USA; Oregon Health & Science University, Department of Urology, Portland, OR, USA. Electronic address:
Objectives: To assess histologic changes in the peritoneal neovagina following RPGAV to better guide shared decision-making regarding vaginoplasty techniques. Robotic-Assisted Peritoneal Flap Gender-Affirming Vaginoplasty (RPGAV) uses pedicled flaps of pelvic peritoneum to form the proximal neovagina. Early reports of peritoneal vaginoplasty suggested potential for "self-lubrication"; however, long-term maintenance of fluid production remains uncertain.
View Article and Find Full Text PDFBioengineering (Basel)
July 2025
Health Science and Wellness Research Center, National Taiwan University, Taipei 10617, Taiwan.
: Residual deficits after early treatment of developmental dysplasia of the hip (DDH) using osteotomy often led to asymmetrical gait deviations with increased repetitive rates of ground reaction force (GRF) in both hips, resulting in a higher risk of early osteoarthritis. This study investigated lower limb inter-joint coordination and swing foot control during level walking in adolescents with early-treated unilateral DDH. : Eleven female adolescents treated early for DDH using Pemberton osteotomy were compared with 11 age-matched healthy controls.
View Article and Find Full Text PDFCancers (Basel)
August 2025
Immunology and Molecular Oncology Diagnostics Unit, Veneto Institute of Oncology IOV-IRCCS, 35128 Padua, Italy.
: Esophageal and esophagogastric junction adenocarcinoma (EADC-EGJA), which mainly develops from Barrett's esophagus (BE), low-grade dysplasia (LGD), and high-grade dysplasia (HGD), has a poor prognosis and several unmet clinical needs, among which is the detection of minimal residual disease (MRD) after endoscopic/surgical resection. Long interspersed nuclear element-1 (LINE-1), a surrogate marker of global methylation, is considered an emerging biomarker for MRD monitoring. The aim of this study was to determine, by LINE-1 methylation analysis, at which carcinogenesis step global methylation is affected and whether this biomarker could be followed in longitudinal to monitor the disease behavior post-surgery.
View Article and Find Full Text PDFActa Chir Orthop Traumatol Cech
July 2025
Arel University, Memorial Atasehir Hospital, Department of Orthopedics and Traumatology, Istanbul, Turkey.
Introduction: This study aimed to present the clinical and radiological results and look for complications of total hip arthroplasty (THA) performed with subtrochanteric transverse femoral shortening osteotomy (STFO) for Crowe type IV developmental dysplasia of the hip (DDH).
Material And Methods: Ninety-four patients who underwent STFO and THA for Crowe type IV DDH between 2013 and 2018 were retrospectively evaluated. The mean follow-up period of the patients was 40 months (range 25 to 55) and the mean operation time was 58 min (range 52 to 70).