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http://dx.doi.org/10.3389/fmicb.2021.832149 | DOI Listing |
Clin Spine Surg
September 2025
Department of Orthopaedic Surgery, Duke University, Durham, NC.
Study Design: Narrative review.
Objective: To synthesize current knowledge on radiographic parameters, classification systems, and compensatory mechanisms essential to the diagnosis and surgical planning of cervical spine deformity (CD) correction.
Summary Of Background Data: CD encompasses a heterogeneous set of conditions associated with neurological impairment and impaired health-related quality of life.
Front Pain Res (Lausanne)
August 2025
Center for Veterinary Medicine, Food and Drug Administration, Rockville, MD, United States.
Annually, millions of humans and animals suffer from chronic and acute pain, creating welfare and quality of life concerns for both humans and animals who suffer this pain. In developing new therapeutic approaches, the challenge is to accurately measure this pain to ascertain the efficacy of novel therapeutics. Additionally, there is a need to develop new and effective analgesic options that may offer alternatives to using opioids that contribute to the opioid epidemic.
View Article and Find Full Text PDFFront Hum Neurosci
September 2025
Department of Neurology, Johns Hopkins School of Medicine, Baltimore, MD, United States.
Primary progressive aphasia (PPA) is a neurological syndrome characterized by the gradual deterioration of language capabilities. Due to its neurodegenerative nature, PPA is marked by a continuous decline, necessitating ongoing and adaptive therapeutic interventions. Recent studies have demonstrated that behavioral therapies, particularly when combined with neuromodulation techniques such as transcranial direct current stimulation (tDCS), can improve treatment outcomes, including the long-term maintenance and generalization of therapeutic effects.
View Article and Find Full Text PDFFront Child Adolesc Psychiatry
August 2025
Faculty of Medicine, Veracruzana University, Minatitlan, Mexico.
Parents of children with autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) face unique challenges that may significantly increase stress levels, potentially impacting the emotional well-being of the entire family. In Mexico, limited research has examined the association between parental stress and coping strategies among families with children with developmental disabilities. This study aimed to compare stress levels and coping strategies among parents of children with ASD, ADHD, and neurotypical developing (NTD) children, as well as to analyze differences in coping styles across these groups.
View Article and Find Full Text PDFJAMIA Open
October 2025
Applied Clinical Research Center, Children's Hospital of Philadelphia, Philadelphia, PA 19104, United States.
Objective: To develop a natural language processing (NLP) pipeline for unstructured electronic health record (EHR) data to identify symptoms and functional impacts associated with Long COVID in children.
Materials And Methods: We analyzed 48 287 outpatient progress notes from 10 618 pediatric patients from 12 institutions. We evaluated notes obtained 28 to 179 days after a COVID-19 diagnosis or positive test.