A microfluidic valve with bubble trap and zero dead volume.

Rev Sci Instrum

Department of Nanobiotechnology, Institute of Biologically Inspired Materials, University of Natural Resources and Life Sciences, Vienna, 1190 Vienna, Austria.

Published: January 2022


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Article Abstract

We present a technique to swiftly change the contents of a small sample chamber using only a few times the chamber volume. Our design has no dead volume and functions as a manifold that minimizes mixing between consecutive liquids at one inlet. Thereby, it is ideal for minimizing sample consumption. In addition, our fluidic circuit works as an efficient bubble trap. These properties make our design an exciting alternative to standard solutions using multiple valves and junctions.

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http://dx.doi.org/10.1063/5.0058259DOI Listing

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