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Objectives: Our goal was to report outcomes of the endovascular repair of urgent thoracoabdominal aortic aneurysms (TAAAs) using the Cook Zenith t-Branch off-the-shelf multibranched endograft.
Methods: Between 2010 and 2020, we collected patients with TAAAs who received an urgent endovascular repair using the Cook Zenith t-Branch (had a rupture, symptoms or diameter >80 mm). Thirty-day mortality, spinal cord ischaemia (SCI) and clinical success were assessed as early outcomes. Freedom from reintervention, target visceral vessel patency and survival were considered during follow-up.
Results: Sixty-five cases were managed using the Cook Zenith t-Branch for 27 (42%) TAAA ruptures, 8 (12%) symptomatic TAAAs and 30 (46%) asymptomatic TAAAs with a diameter >80 mm. Crawford's extent I-II-III and IV were noted in 54 (83%) and 11 (17%), respectively. Eleven (17%) patients had SCI with 3 (5%) cases of permanent paraplegia. Postoperative dialysis (P = 0.04) and ruptured TAAAs (P = 0.05) were associated with SCI. Sixteen (25%) patients had reinterventions within the first 30 days postoperatively. The 30-day mortality was 14% (9). Ruptured TAAAs (P = 0.05) and technical failures (P = 0.01) were correlated with in-hospital mortality. Clinical success was 78% (51 patients). The mean follow-up was 18 ± 14 months. Survival at 24 months was 47% with no late TAAA-related deaths. Patients with ruptured TAAAs had lower survival than those who did not have ruptured TAAAs (52% vs 60% at 1 year; P = 0.05). Target visceral vessel patency and freedom from reintervention at 24 months were 89% and 60%, respectively.
Conclusions: An off-the-shelf multibranched endograft is safe and effective for treating urgent TAAAs. Postoperative SCI and 30-day mortality are satisfactory for this challenging clinical scenario. The early reintervention rate is not negligible. Midterm survival is low, especially in patients with a ruptured TAAA; therefore, accurate patient selection is mandatory.
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http://dx.doi.org/10.1093/ejcts/ezab553 | DOI Listing |
J Vasc Surg
August 2025
Vascular Surgery, Department of Medical and Surgical Sciences (DIMEC), University of Bologna, Bologna, Italy; Vascular Surgery Unit, IRCCS Azienda Ospedaliero-Universitaria di Bologna.
Introduction: Thoracoabdominal aortic aneurysms (TAAA) and juxta/pararenal abdominal aortic aneurysm reported as complex aortic aneurysms (cAAA), represent a technical and clinical challenge with endovascular repair embodying a preferred option for high risk patients. represent a technical and clinical challenge with endovascular repair embodying a preferred option for high risk patients. However, in case of non-elective presentation, both technical and clinical management and outcomes remain limited in Literature.
View Article and Find Full Text PDFJ Vasc Surg
July 2025
Advanced Endovascular Aortic Research Program, Division of Vascular Surgery and Endovascular Therapy, Department of Surgery, Baylor College of Medicine, Houston, TX. Electronic address:
Objective: Type IIIb endoleak (T3bE) owing to fabric tears or integrity issues is infrequent, but has been poorly described among patients undergoing fenestrated-branched endovascular aortic repair (FB-EVAR). This study aimed to describe the incidence, management, and outcomes of T3bE after FB-EVAR for the treatment of complex abdominal aortic aneurysms (CAAAs) and thoracoabdominal aortic aneurysms (TAAAs).
Methods: Clinical data, imaging, and outcomes of consecutive patients enrolled in prospective, nonrandomized physician-sponsored investigational device exemption studies evaluating company-manufactured devices for FB-EVAR at three centers were reviewed from 2013 to 2024.
J Vasc Surg
September 2025
Division of Vascular and Endovascular Surgery, Department of Surgery, University of Texas Southwestern Medical Center, Dallas, TX.
Objective: To report 1-year primary-arm outcomes of the GORE EXCLUDER Thoracoabdominal Branch Endoprosthesis pivotal trial.
Methods: The multicenter, nonrandomized, prospective study included patients with extent IV thoracoabdominal aortic aneurysms (TAAAs) and pararenal aortic aneurysms (PRAAs). All-cause and adjudicated lesion-related mortality were assessed at 12 months.
J Cardiovasc Surg (Torino)
June 2025
Aortic Center, Department of Cardiac and Vascular Surgery, Hôpital Marie Lannelongue, Groupe Hospitalier Paris Saint Joseph, Université Paris-Saclay, Paris, France -
Background: The purpose of this study was to evaluate the outcomes of branched endovascular aortic repair (BEVAR) in post-dissection thoracoabdominal aortic aneurysms (PD TAAAs), as well as define preoperative planning and intraoperative execution.
Methods: Patients who underwent BEVAR in PD TAAAs from 2019 to 2024 were identified using a prospectively maintained electronic database at a single, tertiary-care hospital. Patient demographics, comorbidities, indication for the procedure, anatomic and procedural details, and outcomes were retrospectively recorded.
J Endovasc Ther
March 2025
Unit of Vascular Surgery, Azienda Ospedaliera Santa Maria, Terni, Italy.
Objective: The introduction of off-the-shelf (OTS) multibranch stent-grafts represented an advancement in the endovascular treatment of thoraco-abdominal aortic aneurysms (TAAAs), particularly in urgent settings. In certain cases (e.g, target vessel [TV] occlusion), unused directional branches (DBs) require proper occlusion with a vascular plug to prevent type III endoleaks.
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