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http://dx.doi.org/10.1016/j.jcjo.2021.11.011 | DOI Listing |
Neuroophthalmology
September 2024
Neuro-Ophthalmology Department, King Khaled Eye Specialist Hospital, Riyadh, Saudi Arabia.
We describe a case of unilateral sectoral pigmentation of the optic disc in a healthy 58‑year‑old female who presented with decreased vision and visual field defect in the involved eye since childhood. The patient was initially diagnosed with melanocytoma of the optic nerve given the suggestive clinical appearance. Thorough assessment with magnetic resonance imaging studies, laboratory work-ups and ophthalmic examination indicated that the pigmentation was linked to optic nerve hypoplasia.
View Article and Find Full Text PDFJ Pediatr Urol
August 2025
Ondokuz Mayıs University, Department of Pediatric Surgery, Ondokuz Mayıs Üniversitesi, Kurupelit Kampüsü, Atakum, 55270, Samsun, Turkey. Electronic address:
Introduction: Although rare, incontinent diversions still has a place in the management of challenging conditions. Ureterocutaneostomy (in refluxing or non-refluxing moieties) is a viable option for relief of obstruction. It can be performed open or laaproscopically.
View Article and Find Full Text PDFInvest Ophthalmol Vis Sci
September 2025
Department of Ophthalmology, University of California, Los Angeles, Los Angeles, California, United States.
Purpose: Simulations suggest that displacement of rectus extraocular muscle pulleys in superior oblique (SO) palsy accounts for incomitant strabismus patterns even without postulating SO contractile weakness. We asked how rectus extraocular muscle pulleys reorient during head tilt in SO palsy.
Methods: In 13 subjects with unilateral SO palsy, supine magnetic resonance imaging (MRI) in 2-mm-thick quasi-coronal planes in target-controlled central gaze was repeated in both lateral decubitus positions equivalent to 90° head tilts.
Imaging Neurosci (Camb)
August 2025
KU Leuven, Department of Development and Regeneration, Locomotor and Neurological Disorders group, Leuven, Belgium.
Children with unilateral cerebral palsy (uCP) present with brain damage, predominantly lateralized to one hemisphere, and white matter (WM) lesions, which are known to affect visual functions. However, the relation between WM tract damage and visual outcomes remains unclear. Additionally, no prior study comprehensively investigated hemispheric-specific differences in WM visual pathways between children with left- and right-sided uCP.
View Article and Find Full Text PDFCancer Med
September 2025
Onco-Hematology, Cell Therapy, Gene Therapies and Hemopoietic Transplant, Bambino Gesù Children's Hospital, IRCCS, Rome, Italy.
Introduction: This study presents the outcomes of high-risk group retinoblastoma (Rb) patients enrolled in the AIEOP RTB 012 Protocol.
Methods: Patients with intraocular unilateral Rb classified as group C/D according to "International Intraocular Retinoblastoma Classification" (IIRC), as well as those with bilateral Rb with at least one eye group C/D/E-IIRC, were treated with four cycles of carboplatin/etoposide combined with focal treatments. The primary endpoint was to evaluate ocular event-free survival (EFS) and overall survival (OS), where events were defined as the need for radiotherapy, eye enucleation, and second-line treatment.