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Introduction: The transition of patients across care settings is associated with a high risk of errors and preventable medication-related harm. Ensuring effective communication of information between health professionals is considered important for improving patient safety. A National Health Service(NHS) organisation in the North West of England introduced an electronic transfer of care around medicines (TCAM) system which enabled hospital pharmacists to send information about patient's medications to their nominated community pharmacy. We aimed to understand the adoption, and the implications for sustainable use in practice of the TCAM service.
Methods: We evaluated the TCAM service in a Clinical Commissioning Group (CCG) and NHS Foundation Trust in Salford, United Kingdom (UK). Participants were opportunistically recruited to take part in qualitative interviews through stakeholder networks and during hospital admission, and included hospital pharmacists, hospital pharmacy technicians, community pharmacists, general practice-based pharmacists, patients and their carers. A thematic analysis, that was iterative and concurrent with data collection, was undertaken using a template approach. The interpretation of the data was informed by broad sociotechnical theory.
Results: Twenty-three interviews were conducted with health care professionals patients and carers. The ways in which the newly implemented TCAM intervention was adopted and used in practice and the perceptions of it from different stakeholders were conceptualised into four main thematic areas: The nature of the network and how it contributed to implementation, use and sustainability; The material properties of the system; How work practices for medicines safety were adapted and evolved; and The enhancement of medication safety activities. The TCAM intervention was perceived as effective in providing community pharmacists with timely, more accurate and enhanced information upon discharge. This allowed for pharmacists to enhance clinical services designed to ensure that accurate medication reconciliation was completed, and the correct medication was dispensed for the patient.
Conclusions: By providing pharmacy teams with accurate and enhanced information the TCAM intervention supported healthcare professionals to establish and/or strengthen interprofessional networks in order to provide clinical services designed to ensure that accurate medication reconciliation and dispensing activities were completed. However, the intervention was implemented into a complex and at times fragmented network, and we recommend opportunities be explored to fully integrate this network to involve patients/carers, general practice pharmacists and two-way communication between primary and secondary care to further enhance the reach and impact of the TCAM service.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8694480 | PMC |
http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0261153 | PLOS |
Children (Basel)
July 2025
Department of Physical Education and Sport Science, Aristotle University of Thessaloniki, 54124 Thessaloniki, Greece.
: Motor creativity is a vital component of preschoolers' growth and development. However, its underlying determinants remain largely underexplored. This study investigates the interrelationship among playful behavior, social profile, and motor creativity in preschool children, emphasizing its implications for holistic health and development.
View Article and Find Full Text PDFFront Med (Lausanne)
June 2025
Amrita CREATE, Amrita Vishwa Vidyapeetham, Amritapuri, India.
Introduction: Ayurveda education in India has seen limited integration of learning technology, leading to significant gaps in clinical skill development. This study introduces AyurSIM, a virtual patient simulation platform designed with interactive virtual cases replicating real-world scenarios to address this gap, offering structured educational modules from patient examination through follow-up care, incorporating Ayurveda protocols and a comprehensive database of disease patterns.
Methods: AyurSIM was developed using pedagogical frameworks building on experiential learning, problem-solving tasks, and reflective practice.
Sci Rep
July 2025
Medical Laboratory Center, Chifeng Municipal Hospital/Chifeng Clinical College, Inner Mongolia Medical University, Chifeng, 024000, People's Republic of China.
In the early stage, our research group injected lentivirus carrying blood type A antigen into tumors as a drug, and the tumor volume of mice was significantly reduced. We speculate that the complement system plays an important role in anti-tumor therapy, but the specific components are unknown. A mouse model containing blood type antibodies was established.
View Article and Find Full Text PDFClinics (Sao Paulo)
May 2025
Department of Urology, Hangzhou Children's Hospital, Hangzhou City, Zhejiang Province, PR China. Electronic address:
Objective: The study explored the molecular mechanism of circNOLC1 influencing Testicular Germ Cell Tumor (TGCT) progression.
Methods: The study used TGCT tissue samples and cell lines for investigations. The circNOLC1 and miR-140-5p expression in TGCT tissues were done through RT-qPCR.
Drugs Real World Outcomes
June 2025
School of Pharmacy, University of Auckland, 85 Park Rd, Grafton, Auckland, 1023, New Zealand.
Background: Traditional, complementary and alternative medicine (TCAM), including natural health products (NHPs), are used by many consumers to address their [perceived] health needs. While many developed countries have national data on NHPs use, limited information is available for New Zealand (NZ). Current, robust data on the prevalence and patterns of NHPs use in NZ are required.
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