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Biological Activities and the Essential Oil Analysis of and . | LitMetric

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Article Abstract

This research aimed to evaluate the cytotoxicity, anti-bacterial, anti-fungal and heme polymerization inhibition activities, as well as the detection of the chemical composition of essential oils and measurement of the amount of total phenol and flavonoids of and . growth inhibitory effects of methanol extracts on A2780, T-47D, A549 and Hep-G2 cells were evaluated by MTT assay. MIC and MBC/MFC were determined by the agar dilution method. The anti-malarial activity of herbs was assessed with an inhibition test of heme detoxification (ITHD). Total phenol and flavonoids content measured by Folin-Ciocalteu method. The essential oils from two herbs were extracted by hydro-distillation, and GC/MS analyzed their compositions. Cell studies against selected cell lines growth in MTT assay were related to on Hep-G2 with IC of 4.521 µg/mL. The MIC of anti-bacterial and anti-fungal effects is related to extract on and with 15.62 and 62.5 mg/mL, respectively. Both extracts do not have anti-malarial activity. content was richer in total phenol and flavonoids rather than the other herb. -benzyl benzyl alcohol (46.7%) and butyl phthalate (14.7%) are the major compounds of ; main components of are 3-methyl-tetrahydrofuran (24.6%) and oleic acid (15.4%). In conclusion, with more phenol and flavonoids content showed better results in terms of biological activities.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8653680PMC
http://dx.doi.org/10.22037/ijpr.2020.114155.14697DOI Listing

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