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The interest in the A-stage of the adsorption/bio-oxidation (A/B) process has considerably increased due to its capacity of carbon redirection to the solids stream. Induced by its flexible and compact design, the Alternating Activated Adsorption (AAA) was recently implemented in full-scale as an alternative A-stage system. However, the literature on such a system is scarce. In this article for the first time, the performance of the novel AAA system is evaluated. Two lab-scale AAA systems were operated as a primary settler replacement (AAA-1) or to complement the primary settler (AAA-2). Systems were assessed in terms of process control, effluent quality and carbon diversion. As settling and aeration are performed in the same reactor, AAA maintained high MLSS (2121 ± 293 mg/L for AAA-1 and 806 ± 116 mg/L for AAA-2) compared to the literature at such a very low aerobic SRT (<6 h). Regardless wastewater strength, AAA attains low oxidation (16-17%) owing to the oxygen supply pattern and short aerobic SRT. Moreover, AAA-1 showed high COD removal efficiency for soluble (67 ± 8%) and particulates (62 ± 14%) as well as COD redirection (47 ± 7%). In addition, it is demonstrated that the simultaneous bottom feeding and top discharging regime adds unique capacity for particulates capture in AAA. On the other hand, low particulates removal and total carbon redirection were observed in the AAA-2. Yet, the overall removal efficiencies are comparable with the literature. It can be concluded that, with further optimizations, AAA system has the potential to outcompete other A-stage systems. As such, sludge settleability is found to be challenging when treating low strength wastewater.
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http://dx.doi.org/10.1016/j.jenvman.2021.114172 | DOI Listing |
HRB Open Res
April 2025
General Practice, Royal College of Surgeons in Ireland, Dublin, Leinster, Ireland.
Background: Lung cancer (LC) is the leading cause of cancer death in Ireland, yet no national screening programme exists. While low-dose computed tomography (LDCT) screening reduces lung cancer mortality by approximately 20% in high-risk populations, its cost-effectiveness in Ireland remains uncertain. Evidence on the economic burden of lung cancer care and the feasibility of screening is needed to support policy decisions.
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August 2025
Department of Internal Medicine, CHU de Quebec-Pavillon Hôtel-Dieu de Québec, Université Laval, Quebec City, QC G1R 2J6, Canada.
Systemic Capillary Leak Syndrome (SCLS) and Cytokine Release Syndrome (CRS) have both been described as rare but severe adverse reactions induced by Programmed cell death protein 1 (PD-1) inhibitors such as pembrolizumab. We report the case of a 40-year-old woman undergoing treatment with pembrolizumab for a stage 4 cervical squamous cell carcinoma who presented with anasarca, hypotension, hemoconcentration and signs of multisystemic inflammation. After elimination of alternative causes such as nephrotic syndrome, cardiac dysfunction and cirrhosis, she was diagnosed with both pembrolizumab-induced SCLS and CRS.
View Article and Find Full Text PDFTrends Endocrinol Metab
June 2025
College of Biosystems Engineering and Food Science, National-Local Joint Engineering Laboratory of Intelligent Food Technology and Equipment, Key Laboratory for Agro-Products Nutritional Evaluation of the Ministry of Agriculture and Rural Affairs, Zhejiang University, Hangzhou, China; Zhejiang Unive
Current research on inflammatory disorders tends to focus on the advanced stages of disease; however, acting against chronic low-grade inflammation (a stage before overt disease) through early nutritional interventions may be an alternative, beneficial approach. We systematically evaluate how diet modulates chronic low-grade inflammation through several physiological processes. Furthermore, we suggest three intervention strategies tailored to specific stages of disease: (i) promoting anti-inflammatory dietary patterns in the general population, (ii) implementing precision nutrition targeting inflammatory biomarkers in individuals at risk, and (iii) utilizing adjuvant dietary therapies for existing inflammation.
View Article and Find Full Text PDFPest Manag Sci
August 2025
USDA-ARS, San Joaquin Valley Agricultural Sciences Center, Parlier, CA, USA.
Background: The mealybug Ferrisia gilli Gullan (Hemiptera: Pseudococcidae) has emerged as a major pest on pistachio in California. The indiscriminate use of a select group of chemicals has limited the effectiveness of available options to control F. gilli.
View Article and Find Full Text PDFUpdates Surg
August 2025
Department of General and Digestive Surgery, Hospital Universitari Germans Trias I Pujol, Carretera del Canyet s/n, Badalona, 08916, Barcelona, Spain.
Robotic stapled cardioplasty offers a novel, minimally invasive alternative for treating end-stage achalasia, a rare esophageal motor disorder. Achalasia is characterized by the inability of the lower esophageal sphincter to relax and reduced peristalsis, with about 5% of patients progressing to a stage where esophagectomy is often the only treatment option. This study introduces robotic stapled cardioplasty as a less aggressive, organ-preserving approach.
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