Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Many studies have tested the relationship between demographic, clinical, and psychobiological measurements and clinical outcomes in ultra-high risk for psychosis (UHR) and first-episode psychosis (FEP). However, no study has investigated the relationship between multi-modal measurements and long-term outcomes for >2 years. Thirty-eight individuals with UHR and 29 patients with FEP were measured using one or more modalities (cognitive battery, electrophysiological response, structural magnetic resonance imaging, and functional near-infrared spectroscopy). We explored the characteristics associated with 13- and 28-month clinical outcomes. In UHR, the cortical surface area in the left orbital part of the inferior frontal gyrus was negatively associated with 13-month disorganized symptoms. In FEP, the cortical surface area in the left insula was positively associated with 28-month global social function. The left inferior frontal gyrus and insula are well-known structural brain characteristics in schizophrenia, and future studies on the pathological mechanism of structural alteration would provide a clearer understanding of the disease.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8630202 | PMC |
| http://dx.doi.org/10.1038/s41537-021-00186-9 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Langmuir-Blodgett Films of Conjugated Polymer and Silver Nanoparticles: A Possible Substrate for Pesticide SERS-Based Detection.
Langmuir
September 2025
Federal University of São Paulo, Laboratory of Hybrid Materials, Diadema, São Paulo 09913-030, Brazil.
This study demonstrates the successful fabrication of nanostructured Langmuir-Blodgett (LB) films combining the conjugated copolymer poly(9,9-dioctylfluorene--3,4-ethylenedioxythiophene) (PDOF--PEDOT) with spherical and triangular silver nanoparticles (AgNP). The LB technique allowed precise control over the molecular arrangement and distribution of the nanoparticles at the air-water interface, resulting in compact, reproducible and structurally ordered nanocomposite films. The structural and morphological properties of the interfacial monolayers and LB films were investigated using surface pressure-area isotherms, Brewster angle microscopy, polarization modulation infrared reflection-absorption spectroscopy (PM-IRRAS) and quartz crystal microbalance.
View Article and Find Full Text PDFDual-Analyte Selective Electrochemical Detection of Phenylbutazone and Sulfamethoxazole Using Bio-Engineered BiS-ZnO Nanocomposites.
Langmuir
September 2025
Department of Chemical Engineering, Indian Institute of Technology Guwahati, Guwahati, Assam 781039, India.
Simultaneous sensing and quantification of pharmaceutically active compounds (PhACs) are crucial for protecting the environment and maintaining long-term ecological sustainability. This study focuses on the bio-based synthesis of BiS-ZnO nanocomposites (BiS-ZnO(bio)) using bio-extract for dual-analyte selective and simultaneous electrochemical monitoring of phenylbutazone (PBZ) and sulfamethoxazole (SMZ) in the environmental matrices. BiS-ZnO(bio) exhibited ZnO(bio) nanostructures embedded on BiS(bio) nanorods with an average rod length of 1409.
View Article and Find Full Text PDFTuneable multidirectional mechanical attributes of novel sectionally nonlinearly functionally graded femur and cranial bone implants with triply periodic minimal surfaces.
PLoS One
September 2025
Mechanical and Nuclear Engineering Department, Khalifa University of Science and Technology, Abu Dhabi, United Arab Emirates.
Sectionally nonlinearly functionally graded (SNFG) structures with triply periodic minimal surface (TPMS) are considered ideal for bone implants because they closely replicate the hierarchical, anisotropic, and porous architecture of natural bone. The smooth gradient in material distribution allows for optimal load transfer, reduced stress shielding, and enhanced bone ingrowth, while TPMS provides high mechanical strength-to-weight ratio and interconnected porosity for vascularization and tissue integration. Wherein, The SNFG structure contains sections with thickness that varies nonlinearly along their length in different patterns.
View Article and Find Full Text PDFUnprecedented 2020 coral bleaching reveals unexpected taxa-specific responses in the central Red Sea.
PLoS One
September 2025
Marine Science Program, Biological and Environmental Science and Engineering Division (BESE), King Abdullah University of Science and Technology (KAUST), Thuwal, Kingdom of Saudi Arabia.
Sea surface temperature of the Red Sea has increased by up to 0.45 °C per decade over the last 30 years, and coral bleaching events are becoming more frequent. A reef bleaching event was observed in October 2020, whereby some parts of the Red Sea experienced more than 12 °C-weeks.
View Article and Find Full Text PDFAssessing land surface temperature dynamics and urban heat island effects in Delhi: a multi-temporal analysis and future projections.
Environ Monit Assess
September 2025
Indira Gandhi Conservation Monitoring Centre, World Wide Fund-India, New Delhi, 110003, India.
Understanding the intricate relationship between land use/land cover (LULC) transformations and land surface temperature (LST) is critical for sustainable urban planning. This study investigates the spatiotemporal dynamics of LULC and LST across Delhi, India, using thermal data from Landsat 7 (2001), Landsat 5 (2011) and Landsat 8 (2021) resampled to 30-m spatial resolution, during the peak summer month of May. The study aims to target three significant aspects: (i) to analyse and present LULC-LST dynamics across Delhi, (ii) to evaluate the implications of LST effects at the district level and (iii) to predict seasonal LST trends in 2041 for North Delhi district using the seasonal auto-regressive integrated moving average (SARIMA) time series model.
View Article and Find Full Text PDF