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Introduction: The rapid spread of COVID-19 posed a global burden. Substantial number of people died of the disease in the acute phase of infection. In addition, a significant proportion of patients have been reported to suffer from post-acute phase symptoms, sequelae of COVID-19, which may negatively influence the quality of daily living and/or socioeconomic circumstances of the patients. However, no previous study has comprehensively and objectively assessed the quality of life of patients by using existing international scales. Further, evidence of socioeconomic consequences among patients with COVID-19 is scarce. To address the multidimensional issues from sequelae of COVID-19, evidence from comprehensive surveys beyond clinical perspectives is critical that investigates health, and social determinants of disease progression as well as socioeconomic consequences at a large scale.
Methods And Analysis: In this study, we plan to conduct a nationwide and comprehensive survey for the sequelae of COVID-19 in a total of 1000 patients diagnosed at 27 hospitals throughout Japan. This study will evaluate not only the health-related status of patients from clinical perspectives but also the Health-related Quality of Life (HRQoL) scores, socioeconomic status and consequences to discuss the sequelae of the disease and the related risk factors. The primary endpoint is the frequency of long-term complications of COVID-19 infection. The secondary endpoints are risk factors for progression to sequelae of COVID-19 infection. The study will provide robust and important evidence as a resource to tackle the issues from the sequelae of COVID-19 from the multi-dimensional perspectives.
Ethics And Dissemination: This trial was approved by the Keio University School of Medicine Ethics Committee (20200243, UMIN000042299). The results of this study will be reported at a society meeting or published in a peer-reviewed journal.
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http://dx.doi.org/10.1136/bmjresp-2021-001015 | DOI Listing |
Soc Sci Med
September 2025
Indiana University, Department of Sociology, 1020 E. Kirkwood Ave., Bloomington, IN, 47405, USA.
COVID-19 unleashed a bereavement crisis on a scale unseen in over a century. While evidence suggests COVID-19 deaths are acutely damaging to well-being, it is unclear how multiple losses affect mental health, whether there are ethnoracial differences in cumulative loss, or if the association between multiple COVID-related deaths and psychological distress varies by race-ethnicity. Using national survey data (n = 1810) collected following the Omicron surge in the United States, we estimate a series of regression models to assess the association between multiple COVID-19 losses and psychological distress, racial-ethnic differences in aggregate death exposure, and differential vulnerability to multiple losses across racial-ethnic groups.
View Article and Find Full Text PDFJ Infect Public Health
August 2025
Centers for Disease Control and Prevention, National Center for Immunizations and Respiratory Diseases, Atlanta, GA, USA.
Background: Long COVID, or Post-COVID Conditions (PCC), refers to new and persisting sequelae occurring in the months following an acute SARS-CoV-2 infection. Although previous studies have reported estimates of PCC incidence, few have examined trends during the Omicron variant period or have included geographically distinct regions for the same time periods.
Methods: Track PCC is a surveillance network, leveraging electronic health records and public health data to monitor incidence over time across five diverse geographic sites in the U.
BMJ Open
September 2025
Neath Port Talbot Hospital, Port Talbot, Wales, UK.
Introduction: Gestational diabetes mellitus (GDM) is common in pregnancy and is increasing in prevalence. It is associated with an increased risk of maternal and perinatal complications if not diagnosed and managed early. Most guidelines suggest making a diagnosis of GDM using an oral glucose tolerance test (OGTT) between 24 and 28 weeks of pregnancy at which stage there still is an increased risk of complications.
View Article and Find Full Text PDFJ Bras Nefrol
September 2025
Centro de Asistencia del Sindicato Médico del Uruguay (CASMU), Institución de Asistencia Médica Privada de Profesionales sin fines de lucro (IAMPP), Departamento de Nefrología, Montevideo, Uruguay.
Introduction: Acute kidney disease (AKD) is defined as functional and/or structural abnormalities of kidneys with health implications and a duration of ≤90 days. This study aimed to evaluate AKD as a more appropriate approach to these conditions for which we used a cohort of COVID-19 patients in whom kidney impairment is expressed by proteinuria and/or loss of function.
Methods: Observational, prospective, longitudinal, multinational cohort study conducted across five Latin American countries.
J Drugs Dermatol
September 2025
Background: Alopecia universalis (AU) is the most severe form of alopecia areata (AA), characterized by complete scalp and body hair loss. While post-COVID-19 hair loss is often attributed to telogen effluvium (TE), emerging evidence suggests that COVID-19 may also trigger AU through immune dysregulation, particularly via interferon-gamma (IFN-γ)-mediated inflammation. The chronic and relapsing nature of AU raises challenges in long-term disease management, particularly regarding treatment duration and relapse prevention.
View Article and Find Full Text PDF