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http://dx.doi.org/10.1001/jamapsychiatry.2021.3491 | DOI Listing |
Genome Biol
September 2025
Department of Evolutionary Genetics, Max-Planck Institute for Evolutionary Biology, Plön, Germany.
Background: Most RNA-seq datasets harbor genes with extreme expression levels in some samples. Such extreme outliers are usually treated as technical errors and are removed from the data before further statistical analysis. Here we focus on the patterns of such outlier gene expression to investigate whether they provide insights into the underlying biology.
View Article and Find Full Text PDFEur J Radiol
August 2025
Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Purpose: To evaluate whether AI-assisted ipsilateral tissue matching in digital breast tomosynthesis (DBT) reduces localization errors beyond typical tumor boundaries, particularly for non-expert radiologists. The technology category is deep learning.
Materials And Methods: The study consisted of two parts.
Food Chem
September 2025
Group of Chemical Analysis and Chemometrics, Department of Chemistry, Federal University of Paraná, P.O. Box: 19032, Curitiba, PR 81531-980, Brazil. Electronic address:
Yerba mate, a key crop in South America, is prized for its pleasant taste and high organoleptic quality, often linked to lower branch content. To quantify branch content and authenticate high-quality samples (less than 30 % m/m branch content), a Chemometrics-assisted Color Histogram-based Analytical System (CACHAS) was employed. Using Hue-Saturation-Value (HSV) histograms, Partial Least Squares (PLS) demonstrated excellent predictive performance, achieving a root mean square error (RMSEP) of 4.
View Article and Find Full Text PDFMicrob Genom
September 2025
Department of Infectious Diseases and Public Health, Jockey Club College of Veterinary Medicine and Life Sciences, City University of Hong Kong, Hong Kong, PR China.
African swine fever virus (ASFV) is highly transmissible and can cause up to 100% mortality in pigs. The virus has spread across most regions of Asia and Europe, resulting in the deaths of millions of pigs. A deep understanding of the genetic diversity and evolutionary dynamics of ASFV is necessary to effectively manage outbreaks.
View Article and Find Full Text PDFPLoS One
September 2025
School of Public Health, College of Health Sciences, Makerere University, Kampala, Uganda.
Background: Despite advances in HIV care, viral load suppression (VLS) among adolescents living with HIV (ALHIV) in Uganda continue to lag behind that of adults, even with the introduction of dolutegravir (DTG)-based regimens, the Youth and Adolescent Peer Supporter (YAPS) model, and community-based approaches. Understanding factors associated with HIV viral load non-suppression in this population is critical to inform HIV treatment policy. This study assessed the prevalence and predictors of viral load non-suppression among ALHIV aged 10-19 years on DTG-based ART in Soroti City, Uganda.
View Article and Find Full Text PDF