98%
921
2 minutes
20
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8600569 | PMC |
http://dx.doi.org/10.2147/NSS.S347609 | DOI Listing |
Ann Am Thorac Soc
September 2025
Brigham and Women's Hospital, Division of Sleep and Circadian Disorders, Boston, Massachusetts, United States.
Rationale: There are insufficient data to inform the management of central sleep apnea (CSA) in patients with heart failure (HF) with reduced ejection fraction (HFrEF). Nocturnal oxygen therapy (NOT) has been postulated to benefit CSA patients with HFrEF, but has not been rigorously studied. This article is open access and distributed under the terms of the Creative Commons Attribution Non-Commercial No Derivatives License 4.
View Article and Find Full Text PDFIEEE Trans Neural Syst Rehabil Eng
September 2025
Obstructive sleep apnea (OSA), one of the most common sleep disorders globally, is closely linked to brain function. Resting-state electroencephalography (EEG), due to its convenience, cost-effectiveness, and high temporal resolution, serves as a valuable tool for exploring the human brain function. This study utilized a large cohort with 968 participants who joined in 15-minute daytime resting-state EEG acquisition and overnight polysomnography (PSG) monitoring.
View Article and Find Full Text PDFNat Sci Sleep
September 2025
Department of Neurology, The First Affiliated Hospital of Shandong First Medical University and Shandong Provincial Qianfoshan Hospital, Jinan, Shandong, People's Republic of China.
Objective: This study aimed to identify distinct REM sleep characteristics that differentiate type 1 narcolepsy (NT1) from type 2 narcolepsy (NT2) using polysomnography (PSG), while acknowledging the need for future validation against other hypersomnia disorders.
Methods: A retrospective review included 31 patients with NT1, 21 patients with NT2, and 24 healthy participants. Each participant underwent overnight PSG and a subsequent multiple sleep latency test (MSLT) to assess REM sleep parameters including average REM density, neck myoclonus index, and leg movement index.
Am J Physiol Cell Physiol
September 2025
Department of Cell Biology, University of Pittsburgh, Pittsburgh, PA.
We previously demonstrated the CFTR correctors VX-445 (elexacaftor) and S-VX-121 (vanzacaftor) potentiate heterologously-expressed BK channels, as well as in primary human bronchial epithelial cells (HBEs). This potentiation of BK resulted in altered vasoreactivity and neuronal excitability. We postulated novel compounds could be identified that would potentiate BK while not affecting CFTR.
View Article and Find Full Text PDFHigh temperatures associated with climate change can have adverse effects on wildlife, but behavioural plasticity may buffer such negative effects. Using long-term data from wild dwarf mongooses (), we investigated the impact of high temperatures on daily activity patterns, movement and body mass. On hot days (≥ 35°C) compared with matched cooler ones (≤ 33°C), groups emerged from their overnight sleeping burrow and commenced foraging earlier in the morning and arrived at their overnight sleeping burrow later in the evening.
View Article and Find Full Text PDF