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Study Design: A prospective multicenter study.
Objective: This study aims to investigate the postoperative complications of anterior decompression with fusion (ADF) for the treatment of cervical ossification of the posterior longitudinal ligament (OPLL).
Summary Of Background Data: Surgical treatment for cervical OPLL has a high risk of various complications. ADF is reported to be effective for cervical OPLL, especially for massive OPLL. However, few studies have focused on the surgical complications of ADF.
Methods: We prospectively included 102 patients undergoing ADF for severe cervical OPLL with average canal occupying ratio of 49.8%. We evaluated systemic and local complications, neurological complications, and risk factors related to the postoperative complications.
Results: Frequently observed complications included graft/ implant complications (18.6%), neurological complications (11.8%), and cerebrospinal fluid leak (11.8%). Motor palsy involving only the upper extremity was found in nine patients (8.8%), and other motor palsies involving the lower extremities were found in three patients (2.9%). None of the preoperative factors were significantly associated with the occurrence of neurological palsies, whereas the number of operated levels was a significant factor related to the postoperative graft/implant complications (P = 0.003; odds ratio, 2.112). The incidence of graft/implant complications and related reoperation increased as the number of operated levels increased (especially four levels or more). Most motor palsies were observed immediately after surgery. Of the motor palsies in the bilateral upper extremities and palsies involving the lower extremities, 85.7% showed good recovery, whereas only 40% of unilateral upper extremity motor palsies showed good recovery during the follow-up period.
Conclusion: In ADF for cervical OPLL, the number of operated levels was a significant factor related to the postoperative complication. Specifically, the incidence of graft/implant complications and reoperation rate increased in ADF with four or more levels.Level of Evidence: 3.
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http://dx.doi.org/10.1097/BRS.0000000000004088 | DOI Listing |
Clin Spine Surg
September 2025
Department of Neurosurgery, Neurosurgery, The Walton Centre NHS Foundation Trust, Lower Lane.
Study Design: Retrospective cohort study.
Objective: To characterise patients admitted to a UK tertiary centre with OPLL over a 10-year period.
Summary Of Background Data: OPLL is a progressive degenerative condition that can lead to myelopathy.
Phys Med Biol
September 2025
Peking University, College of Engineering, Beijing, Beijing, 100871, CHINA.
Objective: Ossification of the posterior longitudinal ligament (OPLL) is a prevalent cervical spine degeneration disease leading to significant spinal cord dysfunctions. Due to morphological diversity and data scarcity, traditional OPLL assessment relies on manual measurements, which suffer from low consistency and high cost. To implement automated quantification of the OPLL, a cognition-inspired segmentation framework, named the probabilistic anatomical cognition (PAC) framework, is proposed to encode physicians' anatomical knowledge of the OPLL and mimic their hierarchical logic of inferring lesions.
View Article and Find Full Text PDFSpine J
August 2025
Department of Neurosurgery, The Walton Centre NHS Foundation Trust, Liverpool, United Kingdom; University of Liverpool, Liverpool, United Kingdom. Electronic address:
Background Context: Degenerative cervical myelopathy (DCM) is the commonest cause of spinal cord dysfunction. The optimal surgical approach for multilevel DCM (MDCM) remains debated.
Purpose: To assess functional, patient-reported, and surgical-related outcomes of anterior and posterior surgical approaches for MDCM.
Front Surg
August 2025
Department of Orthopedics, Beijing Tongren Hospital, Capital Medical University, Beijing, China.
Objective: This study aims to retrospectively analyze 104 patients diagnosed with cervical spinal cord injury without fracture or dislocation (CSCIwoFD) who underwent surgical treatment, in order to compare the effects of early vs. delayed surgical intervention on neurological functional recovery.
Methods: Patients diagnosed with CSCIwoFD and treated surgically at our institution between August 2020 and January 2023 were retrospectively reviewed.
Clin Spine Surg
August 2025
Spine Center, Department of Orthopaedics, Shanghai Changzheng Hospital, Second Affiliated Hospital of Naval Medical University.
Study Design: A retrospective cohort study.
Objective: The study aimed to explore the expression difference of inflammatory cells in patients with ossification of the posterior longitudinal ligament (OPLL) of the cervical spine and investigate the expression level of IL-6, IL-1β, MCP-1, TNF-α, RANTES, and IL-10 in patients with OPLL.
Background: Ossification of the posterior longitudinal ligament (OPLL) is a disease that can seriously affect spinal cord and nerve function.