98%
921
2 minutes
20
We introduce perturbative spatial frequency domain imaging (p-SFDI) for fast two-dimensional (2D) mapping of the optical properties and physiological characteristics of skin and cutaneous microcirculation using spatially modulated visible light. Compared to the traditional methods for recovering 2D maps through a pixel-by-pixel inversion, p-SFDI significantly shortens parameter retrieval time, largely avoids the random fitting errors caused by measurement noise, and enhances the image reconstruction quality. The efficacy of p-SFDI is demonstrated by imaging forearm of one healthy subject, recovering the 2D spatial distribution of cutaneous hemoglobin concentration, oxygen saturation, scattering properties, the melanin content, and the epidermal thickness over a large field of view. Furthermore, the temporal and spatial variations in physiological parameters under the forearm reactive hyperemia protocol are revealed, showing its applications in monitoring temporal and spatial dynamics.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8547977 | PMC |
http://dx.doi.org/10.1364/BOE.428243 | DOI Listing |
Wounds
August 2025
Department of Day Surgery, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorder, Chongqing, China; China International Science and Technology Coopera
Background: Current management of pediatric cutaneous abscesses involves either spontaneous healing by secondary intention or suturing through tertiary intention, which are often lengthy processes that cause discomfort and distress among children. As it is noninvasive and simple, a novel zipper device is widely used for the primary wound closure of surgical incisions.
Objective: To describe the effectiveness of novel zipper device use for pediatric cutaneous abscess wound closure in an outpatient context.
Clin Lymphoma Myeloma Leuk
August 2025
Dermatology Service, Department of Medicine, Memorial Sloan Kettering Cancer Center, New York, NY. Electronic address:
Background: Mogamulizumab is more effective in treating the blood component of mycosis fungoides (MF) and Sezary syndrome (SS), though some patients also experience significant skin improvement. The characteristics distinguishing those with a favorable skin response remain unclear.
Objectives: This study aimed to characterize MF/SS patients achieving skin response on mogamulizumab.
Br J Anaesth
September 2025
MSk Lab, Imperial College London, London, UK; Theatres and Anaesthetics, Imperial College Healthcare NHS Trust, London, UK. Electronic address:
Background: The mechanisms contributing to epidural-related maternal hyperthermia remain unclear. One explanation is that blockade of cholinergic sympathetic nerves prevents active vasodilation and sweating. However, it is not known how labour epidural analgesia affects cutaneous sympathetic function.
View Article and Find Full Text PDFBr J Haematol
September 2025
Platform of Molecular Analysis for Mastocytosis and MCAD (CEREMAST), Department of Biological Hematology, Pitié-Salpêtrière Hospital, AP-HP, Paris Sorbonne University, Paris, France.
Mastocytosis is categorized into cutaneous mastocytosis (CM), mast cell sarcoma and systemic mastocytosis (SM). Within SM, indolent SM (ISM) is the more frequent subtype. Adult patients with CM but without an extracutaneous biopsy are classified as having mastocytosis in the skin (MIS), a provisional diagnosis.
View Article and Find Full Text PDFTravel Med Infect Dis
September 2025
Department of Veterinary Biosciences, Melbourne Veterinary School, The University of Melbourne, Parkville, Victoria 3010, Australia.
Background: Cutaneous myiasis is an ectoparasitic disease caused by fly larvae. In non-endemic regions it is rare, often unfamiliar to clinicians and readily misdiagnosed.
Case Presentation: A 24-year-old Serbian traveller developed painful furuncular lesions on the thigh after returning from Kenya.