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Rationale: Pulmonary foreign body aspiration is a serious medical problem. The risk of foreign body aspiration into the airways increases considerably in patients with end stage cancer with reduced consciousness and impaired airway reflexes. However, few studies have reported on foreign body aspiration in the airways in patients with terminal cancer or receiving end-of-life care. Herein, we report the use of flexible bronchoscopy in patients with end-of-life cancer with pulmonary aspiration.
Patient Concerns: A 71-year-old man with neuroendocrine carcinoma was admitted to a palliative care unit for end-of-life care. He accidentally aspirated implant teeth into the airway with decreased consciousness and death rattle.
Diagnosis: On chest x-ray, the foreign material was observed in the left main bronchus.
Interventions: Despite concerns regarding the use of bronchoscopy given the deterioration of the overall organ function, flexible bronchoscopy was performed.
Outcomes: Eventually, the foreign body was removed using a basket in the nasal cavity without major complications. The patient died comfortably after 7 days.
Lessons: The possibility of patients in the palliative care unit with reduced consciousness and death rattle to aspirate foreign bodies into the airways must be carefully considered. Flexible bronchoscopy should be considered to carefully remove aspirated foreign bodies in the airway without any side effects, even in patients with terminal cancer or receiving end-of-life care.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8556047 | PMC |
http://dx.doi.org/10.1097/MD.0000000000027620 | DOI Listing |
Interv Radiol (Higashimatsuyama)
August 2025
Department of Radiology, Mie University Hospital, Japan.
Disruption of the central venous port catheter was identified on the chest radiograph of a 36-year-old woman who had undergone chemotherapy following resection of her colon cancer. Computed tomography revealed that the catheter was impacted in the peripheral pulmonary artery. Instead of using a snare wire, a balloon catheter was inserted into the lumen of the disrupted catheter due to its tight lodging in the pulmonary artery.
View Article and Find Full Text PDFJ Surg Case Rep
September 2025
Department of Pediatric Surgery, International Medical Center, Hail Street, AL-Ruwais, Jeddah 23214, Saudi Arabia.
Foreign body ingestion in children, especially those aged 6 months to 3 years, is a common clinical concern. While most objects pass through the gastrointestinal tract uneventfully, some may result in obstruction and necessitate surgical intervention. We report a rare case of a 10-year-old child with autism who presented with small bowel obstruction following ingestion of a rubber feeding bottle nipple.
View Article and Find Full Text PDFJ Control Release
September 2025
Department of Bioengineering, Rice University, Houston, TX, USA. Electronic address:
The development of continuous-release devices or injectables for the long-term delivery of biologics is of great interest, especially monoclonal antibodies (mAbs) that require frequent, high-dose injections. Preclinical testing of these technologies in murine models is necessary for clinical translation; however, xenogeneic responses to the mAb and foreign body responses to the implants or injectables can confound results. Immune system knockout (KO) models that affect immune cells are often used in these experiments, but the effects of KO models on mAb pharmacokinetics (PK) are not well characterized.
View Article and Find Full Text PDFBiosens Bioelectron
September 2025
Microtechnology for Neuroelectronics Unit (NetS(3) lab), Fondazione Istituto Italiano di Tecnologia, Genova, Italy.
Achieving stable and continuous monitoring of signals of numerous single neurons in the brain faces the conflicting challenge of increasing the microelectrode count while minimizing cross-sectional shank dimensions to reduce tissue damage, foreign-body-reaction and maintain signal quality. Passive probes need to route each microelectrode individually to external electronics, thus increasing shank size and tissue-damage as the number of electrodes grows. Active complementary metal-oxide-semiconductor (CMOS) probes overcome the limitation in electrode count and density with on-probe frontend, addressing and multiplexing circuits, but current probes have relatively large shank widths of 70 - 100 μm.
View Article and Find Full Text PDFForensic Sci Med Pathol
September 2025
Chair and Department of Forensic Medicine, Medical University of Lublin, Lublin, 8B Jaczewskiego st, 20-090, Poland.
This study presents a medico-legal case study of an infant who died as a result of intestinal volvulus, a rare but severe complication secondary to the ingestion of multiple magnets and button batteries. The mutual attraction of magnets through adjacent intestinal loops, compounded by the corrosive effects of button batteries, can precipitate rapid and irreversible damage to the gastrointestinal wall. A comprehensive review of the literature on documented pediatric cases involving the ingestion of magnets and button batteries was undertaken to compare the spectrum and frequency of complications.
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