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Necrotizing enterocolitis (NEC) is a leading cause of death in very preterm born infants. The most severe variant is NEC totalis (NEC-T), where necrosis of the small intestines is so extensive that curative care is often withdrawn. Mortality and NEC-T are difficult to predict before surgery, complicating counseling and decision-making.

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Complete Resection of Necrotic Bowel Improves Survival in NEC Without Compromising Enteral Autonomy.

J Pediatr Surg

February 2024

Evelina London Children's Hospital, London, United Kingdom; Faculty of Life Sciences & Medicine, King's College London, London, United Kingdom.

Aims: Controversy persists regarding operative strategy for necrotising enterocolitis (NEC). Some surgeons advocate resecting all necrotic bowel, whilst others defunction with a stoma, leaving diseased bowel in situ to preserve bowel length. We reviewed our institutional experience of both approaches.

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Survey on surgical treatment of neonatal necrotizing enterocolitis in China 2022.

World J Pediatr Surg

August 2023

Department of Neonatal Surgery, Children's Hospital, Zhejiang University School of Medicine, Hangzhou, China.

Objective: The aim of this study was to identify the state of surgical treatment of neonatal necrotizing enterocolitis (NEC) in China.

Methods: A total of 246 delegates (88.0% senior surgeons) completed a survey sent by the Neonatal Surgery Group of the Pediatric Surgery Branch of the Chinese Medical Association in 2022.

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Updates and recommendations on the surgical management of NEC.

Semin Perinatol

February 2023

Chief, Program Director, Division of Pediatric Surgery, , Oklahoma Children's Hospital, University of Oklahoma Health Sciences Center (OUHSC), 1200 Everett Drive, ET NP 2320, Oklahoma City, OK 73104, United States. Electronic address:

Necrotizing enterocolitis is a severe gastrointestinal disease of the infant. It most commonly targets those that are born prematurely. NEC has been associated with initiation of feeds and in most cases, it can be managed with antibiotics and bowel rest.

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Purpose: Necrotizing enterocolitis (NEC) totalis is a devastating disease of the newborn intestine. A precise clinical definition of the extent of gastrointestinal involvement is lacking in the existing literature, and the clinical outcomes are typically viewed as grim.

Methods: Herein, we present a series of clinical case examples of patients with varying degrees of NEC totalis and other co-morbid conditions, with possible anticipated outcomes based on current data.

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