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http://dx.doi.org/10.1186/s12967-021-02866-7 | DOI Listing |
Neuro Oncol
September 2025
Department of Radiation Oncology, Mayo Clinic, Rochester, MN, USA.
Background: Disruption of the blood-brain barrier (BBB) in high-grade brain tumors is characterized by contrast accumulation on diagnostic imaging. This window of opportunity study correlates contrast imaging features with the tumor distribution of BBB-permeable (levetiracetam) and -impermeable (cefazolin) drugs.
Methods: Patients with a clinical diagnosis of a high-grade brain tumor underwent MRI for surgical planning.
Hum Reprod Update
September 2025
Women's Health Research Collaborative, New York, NY, USA.
Background: Reproductive-age women with intrauterine adhesions (IUAs) following uterine surgery may be asymptomatic or may experience light or absent menstruation, infertility, preterm delivery, and/or peripartum hemorrhage. Understanding procedure- and technique-specific risks and the available evidence on the impact of surgical adjuvants is essential to the design of future research.
Objective And Rationale: While many systematic reviews have been published, most deal with singular aspects of the problem.
Soc Psychiatry Psychiatr Epidemiol
September 2025
Centre for Global Mental Health, Health Service and Population Research Department, Institute of Psychiatry, Psychology and Neuroscience, King's College London, London, UK.
Purpose: Understanding the mechanisms through which poverty influences perinatal depression can provide insight into how to develop interventions to improve maternal mental health. To address this question, we aim to estimate indirect effects of important mediators on the causal relationship between food insecurity and symptoms of postnatal depression.
Methods: We used data from the control arm of the Africa Focus on Intervention Research for Mental health - South Africa (AFFIRM-SA) trial that included pregnant women with perinatal depression.
Disabil Rehabil Assist Technol
September 2025
School of Foreign Languages, Ningbo University of Technology, Ningbo, China.
The speech and language rehabilitation are essential to people who have disorders of communication that may occur due to the condition of neurological disorder, developmental delays, or bodily disabilities. With the advent of deep learning, we introduce an improved multimodal rehabilitation pipeline that incorporates audio, video, and text information in order to provide patient-tailored therapy that adapts to the patient. The technique uses a cross-attention fusion multimodal hierarchical transformer architectural model that allows it to jointly design speech acoustics as well as the facial dynamics, lip articulation, and linguistic context.
View Article and Find Full Text PDFJ Surg Res
September 2025
Department of Surgery, University of Texas Medical Branch (UTMB), Galveston, Texas; Department of Surgery, Brigham and Women's Hospital, Boston, Massachusetts.
Introduction: Feedback plays a pivotal role in surgical training. Gamification offers a way to make the feedback process more efficient by automating and expediting feedback delivery, which might otherwise be difficult to provide. Prior data suggest that negative feedback may play a greater role in improving performance on laparoscopic skills tasks, whereas positive feedback may enhance learner satisfaction, confidence, and engagement.
View Article and Find Full Text PDF