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The STRONG STAR Consortium (South Texas Research Organizational Network Guiding Studies on Trauma and Resilience) and the Consortium to Alleviate PTSD are interdisciplinary and multi-institutional research consortia focused on the detection, diagnosis, prevention, and treatment of combat-related posttraumatic stress disorder (PTSD) and comorbid conditions in military personnel and veterans. This manuscript outlines the consortia's state-of-the-science collaborative research model and how this can be used as a roadmap for future trauma-related research. STRONG STAR was initially funded for 5 years in 2008 by the U.S. Department of Defense's (DoD) Psychological Health and Traumatic Brain Injury Research Program. Since the initial funding of STRONG STAR, almost 50 additional peer-reviewed STRONG STAR-affiliated projects have been funded through the DoD, the U.S. Department of Veterans Affairs (VA), the National Institutes of Health, and private organizations. In 2013, STRONG STAR investigators partnered with the VA's National Center for PTSD and were selected for joint DoD/VA funding to establish the Consortium to Alleviate PTSD. STRONG STAR and the Consortium to Alleviate PTSD have assembled a critical mass of investigators and institutions with the synergy required to make major scientific and public health advances in the prevention and treatment of combat PTSD and related conditions. This manuscript provides an overview of the establishment of these two research consortia, including their history, vision, mission, goals, and accomplishments. Comprehensive tables provide descriptions of over 70 projects supported by the consortia. Examples are provided of collaborations among over 50 worldwide academic research institutions and over 150 investigators.
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http://dx.doi.org/10.1016/j.cct.2021.106583 | DOI Listing |
Phys Rev Lett
August 2025
Università degli Studi di Padova, Dipartimento di Fisica e Astronomia, Via Marzolo 8, 35131 Padova, Italy.
Feebly interacting particles, such as sterile neutrinos, dark photons, and axions, can be abundantly produced in the proto-neutron star (PNS) formed in core-collapse supernovae (CCSNe). These particles can decay into photons or charged leptons, depositing energy outside the PNS. Strong bounds on new particles can thus be derived from the observed luminosity of CCSNe, with even tighter bounds obtained from low-energy SNe observations.
View Article and Find Full Text PDFPhys Rev Lett
August 2025
Frankfurt Institute for Advanced Studies FIAS, Frankfurt 60438, Germany.
Partonic collectivity is one of the necessary signatures for the formation of quark-gluon plasma in high-energy nuclear collisions. Number of constituent quarks (NCQ) scaling has been observed for hadron elliptic flow v_{2} in top energy nuclear collisions at the Relativistic Heavy Ion Collider and the LHC, and this has been theoretically suggested as strong evidence for partonic collectivity. In this Letter, a systematic analysis of v_{2} of π^{±}, K^{±}, K_{S}^{0}, p, and Λ in Au+Au collisions at sqrt[s_{NN}]=3.
View Article and Find Full Text PDFESMO Open
September 2025
Aminex Therapeutics, Inc., Kenmore, USA. Electronic address:
Background: Dysregulation of polyamine synthesis has been observed in various cancer cell types. A novel approach to depriving cancer cells of polyamines involves the use of difluoromethylornithine (DFMO) to block polyamine biosynthesis in combination with AMXT 1501, a potent inhibitor of polyamine transport. Preclinical mouse tumor models showed that the combination of AMXT 1501 plus DFMO had strong antitumor activity, together with evidence of a stimulated immune response against tumors.
View Article and Find Full Text PDFACS Nano
September 2025
Department of Physics, National University of Singapore, Singapore 117551, Singapore.
Two-dimensional ferroelectrics with large out-of-plane polarization (OOP) are promising for the design of low-power memory and logic devices, but their experimental realization remains limited due to the scarcity of homobilayers and the complexity of heterobilayers. Here, we perform high-throughput screening of 24,960 configurations and identify 43 semiconducting heterobilayer ferroelectrics with an OOP exceeding the experimentally reported value in MoS/WS while maintaining sliding barriers below 100 meV/f.u.
View Article and Find Full Text PDFBiology (Basel)
August 2025
Center of Excellence in Biodiversity Research, Mahasarakham University, Maha Sarakham 44150, Thailand.
is a phytophagous insect widely distributed across Asia, Europe, and Africa, yet its genetic variation remains poorly understood. This study presents the first comprehensive analysis of the genetic diversity and structure of in Thailand using mitochondrial cytochrome c oxidase subunit 1 () sequences from 202 individuals across 27 localities. A total of 58 haplotypes were identified, with high haplotype and nucleotide diversity observed, suggesting substantial genetic variation.
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