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Objective: Evaluation of the behavior of three different bulk-filling techniques in terms of internal adaptation and external marginal sealing for restoring class II cavities.
Methods: Fifteen extracted sound molar teeth were used. Two standardized class II mesio/disto-occlusal (MO/DO) slot cavities, 4 mm long, 4 mm wide and 3 mm deep were prepared in each tooth, obtaining n=30 cavity preparations. The cavities were randomly assigned into three groups (n=10 per group) according to three bulk filling techniques: Bulk Traditional (BT), Bulk&Go (BG) and Bulk&Flow (BF). The teeth were analyzed by scanning electron microscopy (SEM) to investigate the external marginal seal. Thereafter, the chemical composition of tooth-restoration interface was analyzed by energy-dispersive X-ray spectroscopy (EDS). Complementary information to the SEM and EDS were obtained by micro-computed tomography (μCT) to assess the internal fit.
Results: SEM analysis showed a proper external marginal seal for all groups tested as confirmed by the EDS investigation, highlighting the presence of adhesive layer at the tooth-restoration interface. The internal marginal adaptation by means of μCT analysis revealed gaps formation at the tooth-restoration interface only for BT group, while an intimate contact free of gaps were found in the other two groups. Moreover, in BT and BF groups voids were present within the restoration.
Significance: BG and BF techniques can be considered as reliable alternatives to BT technique, as they simplify the class II restoration without transforming it into class I, thus ensuring a successful result.
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http://dx.doi.org/10.1016/j.jmbbm.2021.104812 | DOI Listing |
Am J Ophthalmol
September 2025
Department of Ophthalmology, Xin Hua Hospital Affiliated to Shanghai Jiao Tong University School of Medicine, Shanghai, China. Electronic address:
Objective: To examine the safety and effectiveness of non-inverted ILM Free Flap combined with the SPOT technique (Sub-Perfluorocarbon liquid (PFCL) injection of Ocular viscoelastic device (OVD) Technique) in the treatment of unclosed macular holes (MHs).
Design: Retrospective interventional case series.
Participants: Eight patients (8 eyes) with persistent unclosed MHs were treated at a tertiary eye hospital in China from September 2023 to February 2025.
Eur J Surg Oncol
July 2025
General Surgery Unit, Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, PISA, Italy.
Introduction: Surgery for resectable gallbladder cancer (GbC) encompasses complex operative management, and evaluating surgical quality through textbook outcome (TO) is crucial. This study aimed to assess TO incidence and impact in a global cohort, identify independent predictors, and evaluate TO rates of minimally invasive (MI) techniques, including robotic (ROB) and laparoscopic (LPS).
Materials And Methods: This cohort study included patients undergoing curative-intent hepatectomy and lymphadenectomy for GbC (T1b-T3) from 2012 to 2023 in 41 hospitals.
Front Public Health
September 2025
Institute of Physical Education, Sichuan University, Chengdu, China.
Objective: This study aimed to examine the relationship between physical activity volume and sleep duration in older adults, using objective monitoring data to investigate their non-linear association and threshold effects, thereby providing references for developing exercise programs to improve sleep duration.
Methods: The study used two consecutive waves of NHANES cross-sectional data (2011-2014) as the derivation cohort and NHANES 2005-2006 data as the validation cohort. Analysis of the derivation cohort included weighted univariate analysis, weighted multivariate logistic regression, and interpretable machine learning analysis.
Front Oncol
August 2025
Department of Urology, Beijing Chaoyang Hospital, Capital Medical University, Beijing, China.
Objective: To explore the prognostic value of preoperative hematological indicators for prostate cancer (PCa) patients with laparoscopic radical prostatectomy (LRP) and construct a nomogram prediction model based on hematological indicators and clinicopathological characteristics.
Method: PCa patients who underwent LRP in Beijing Chaoyang Hospital from January 2017 to December 2022 were retrospectively analyzed. Clinicopathological data and blood indicators, including the neutrophil-to-lymphocyte ratio (NLR), platelet-to-lymphocyte ratio (PLR), lymphocyte-to-monocyte ratio (LMR), red blood cell distribution width (RDW), prognosis nutritional index were compared between non-recurrence and recurrence groups.
Facial Plast Surg
September 2025
ENT Department, San Giuseppe Moscati Hospital District, Aversa, Italy.
Introduction: Managing nasal tip support and lateral crura malposition remains a challenge in rhinoplasty. Objectives & Hypotheses: This study aimed to evaluate the effectiveness of a novel suture technique-the Pulley-Stitch-in correcting lateral crura malposition.
Primary Outcome: change in lateral crura angle; secondary outcome: long-term stability.