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http://dx.doi.org/10.1016/j.jfma.2021.08.019 | DOI Listing |
Naunyn Schmiedebergs Arch Pharmacol
September 2025
Department of Pharmacology, All India Institute of Medical Sciences (AIIMS), Bhubaneswar, India.
Clozapine, the only drug approved by the FDA for treatment-resistant schizophrenia, operates within a narrow therapeutic range (0.35-0.60 mg/mL) and requires titration from 12.
View Article and Find Full Text PDFFront Psychiatry
August 2025
Department of Psychology, University of Rochester, Rochester, NY, United States.
Introduction: Within healthcare settings, schizophrenia spectrum disorder (SSD) stigma is pervasive and presents significant barriers to recovery and equitable care. Understanding the sources, nature, and moderators of such stigma among healthcare providers is essential for informing targeted interventions.
Methods: We conducted a systematic review of 44 peer-reviewed studies examining SSD-related stigma among diverse healthcare providers, including trainees, nurses, general practitioners, psychiatrists, psychologists, and community health workers.
Mol Psychiatry
September 2025
Department of Pharmacological and Biomolecular Sciences "Rodolfo Paoletti", Università degli Studi di Milano, Milan, Italy.
Early-life experiences shape neural networks, with heightened plasticity during the so-called "sensitive periods" (SP). SP are regulated by the maturation of GABAergic parvalbumin-positive (PV+) interneurons, which become enwrapped by perineuronal nets (PNNs) over time, modulating SP closure. Additionally, the opening and closing of SP are orchestrated by two distinct gene clusters known as "trigger" and "brake".
View Article and Find Full Text PDFTurk J Pediatr
September 2025
Department of Child and Adolescent Psychiatry, Ankara Bilkent City Hospital, Faculty of Medicine, Ankara Yıldırım Beyazıt University, Ankara, Türkiye.
Background: Intractable paroxysmal sneezing is a rare and diagnostically challenging condition in children, often mimicking organic diseases. While it is often addressed as psychogenic in the literature, our case presented findings suggestive of a tic disorder, highlighting the need for a broader diagnostic perspective.
Case Presentation: An 11-year-old girl was referred to the child and adolescent psychiatry clinic with a one-year history of persistent and fluctuating sneezing episodes.
PLoS One
September 2025
Yale Program for Recovery and Community Health (PRCH), New Haven, Connecticut, United States of America.
Background: Rates of acute myocardial infarction (AMI) morbidity and mortality have increased in young women aged ≤55 years but little is known about their experience recovering from and living with AMI. A personal recovery (experience of an identity shift manifested in both losses and gains) has been reported among general AMI survivors. Our objective was to gain insights into young women's perspectives on long-term post-AMI recovery, under the patient-centered personal recovery framework.
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