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http://dx.doi.org/10.21037/acs-2020-rp-229 | DOI Listing |
Endocr Connect
September 2025
Centre for Higher Education Development, University of Cape Town.
Background: Cortisol and growth hormone are important for sleep regulation and cognition. Sleep is critical for cognitive functioning, and memory consolidation. Patients with pituitary disease experience hormonal dysregulation, impaired sleep quality, and cognitive dysfunction.
View Article and Find Full Text PDFJ Arthroplasty
September 2025
Department of Orthopaedic Surgery, Emory University School of Medicine, 21 Ortho Lane, Atlanta, GA, 30329.
Background: In cases of isolated, single-compartment osteoarthritis of the knee, both unicompartmental knee arthroplasty (UKA) and total knee arthroplasty (TKA) can be effective treatment options. This study evaluated rates of technology-assisted utilization in UKA (TA-UKA) using a national claims database over a contemporary 13-year period to determine the trends in use of TA-UKA relative to TKA in the United States.
Methods: Patients undergoing primary UKA and TKA from 2009 to 2022 were identified using a large national claims database.
PLoS One
September 2025
School of Health & Society, University of Salford, Salford, Greater Manchester, United Kingdom.
Background: Velocity-Based Training (VBT) is an emerging method in resistance training for objectively prescribing and monitoring training intensity and neuromuscular function. Given its growing popularity, assessing the validity and reliability of VBT devices is critical for strength and conditioning coaches.
Objective: The primary purpose of this review was twofold: (1) to identify and address methodological gaps in current assessments of VBT device validity and reliability, and (2) to propose and apply a novel, multi-layered, criterion-based framework-developed in collaboration with statisticians and domain experts-for evaluating these devices.
Plast Surg (Oakv)
September 2025
Division of Plastic Surgery, Department of Surgery, Dalhousie University, Halifax, Canada.
Emergency department (ED) visits following elective surgeries place significant strain on already overburdened healthcare systems. In Nova Scotia, carpal tunnel release (CTR) and trigger finger release (TFR) are the most common elective hand surgeries performed. This study sought to determine the rates, reasons, and risk factors associated with ED visits following elective outpatient hand surgery.
View Article and Find Full Text PDFGenet Med
September 2025
Division of Genetics and Epidemiology, The Institute of Cancer Research, London, UK; The Royal Marsden NHS Foundation Trust, Fulham Road, London, UK. Electronic address:
Purpose: Hereditary Leiomyomatosis and Renal Cell Cancer (HLRCC) is a rare cancer susceptibility syndrome exclusively attributable to pathogenic variants in FH (HGNC:3700). This paper quantitatively weights the phenotypic context (PP4/PS4) of such very rare variants in FH.
Methods: We collated clinical diagnostic testing data on germline FH variants from 387 individuals with HLRCC and 1,780 individuals with renal cancer, and compared the frequency of 'very rare' variants in each phenotypic cohort against 562,295 population controls.