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Purpose: The purpose of our study was to determine the risk factors for reduction loss in patients with proximal humeral fractures after locking plate fixation and establish a nomogram prediction model.
Methods: We retrospectively analyzed the clinical data of proximal humeral fractures patients who had been surgically treated for locking plate in our institution from January 2016 to December 2018. Perioperative information was obtained through the electronic medial record system, univariate and multivariate analyzes were performed to determine the risk factors of reduction loss, and a nomogram model was constructed to predict the risk of reduction loss. The predictive performance and consistency of the model were evaluated by the consistency coefficient (C-index) and the calibration curve, respectively.
Results: 115 patients were finally enrolled in our study. Multivariate analysis results showed that age, fracture classification, medial comminution, and calcar screw status were independent risk factors for reduction loss. The accuracy of the contour map for predicting transfusion risk was 0.944.
Conclusion: We found a correlation between reduction loss and age, fracture classification, medial comminution, and calcar screw status after locking plate fixation for proximal humeral fractures patients. Our nomogram is helpful for clinicians to identify high-risk patients, early intervention and reduce the incidence of reduction loss.
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http://dx.doi.org/10.1016/j.injury.2021.07.041 | DOI Listing |
J Appl Physiol (1985)
September 2025
Department of Kinesiology and Sport Management, Texas Tech University, Lubbock, Texas, United States of America.
Consistent sleep patterns are associated with better cardiovascular health, while sleep loss is known to impair vascular function. This study examined whether consistent sleep could improve vascular function and mitigate the negative effect of 25-hour total sleep deprivation. Sixteen healthy adults (10 females, 6 males; 34 ± 9 years; BMI: 25 ± 3 kg/m²) completed a randomized crossover study involving two 12-night sleep conditions, habitual sleep and a consistent sleep/wake schedule that were separated by a 1-2-week washout.
View Article and Find Full Text PDFJ Org Chem
September 2025
Department of Chemistry, University of Rochester, 120 Trustee Road, Rochester, New York 14627, United States.
This report presents the alkynyl -Prins cyclization of Achmatowicz adducts, enabling the synthesis of up to 24 (24) highly functionalized [4.3.1] and [3.
View Article and Find Full Text PDFJ Med Internet Res
September 2025
Institute of Social Medicine, Occupational Health and Public Health (ISAP), Medical Faculty, University of Leipzig, Leipzig, Germany.
Background: The loss of a loved one is a common yet stressful event in later life. Internet- and mobile-based interventions have been proposed as an effective treatment approach for individuals with prolonged grief.
Objective: The AgE-health study aimed to investigate the efficacy of an eHealth intervention, trauer@ktiv, in reducing prolonged grief symptoms in a sample of older adults.
Biochem Genet
September 2025
Department of General Surgery, The Second People's Hospital & Nantong Rehabilitation Hospital, No. 298, Xinhua Road, Nantong, 226001, Jiangsu, China.
To evaluate the expression of hsa_circ_0077007 in the serum of colorectal cancer (CRC) patients and offer a foundational theory for the prognosis of CRC. The present study focuses on investigating the biological function and therapeutic target of hsa_circ_0077007 in colorectal cancer CRC. Retrieve the GEO database and use the GEO2R tool to analyze the GSE dataset (GSE223001 and GSE159669) to obtain aberrantly expressed circRNAs.
View Article and Find Full Text PDFJ Cosmet Dermatol
September 2025
Department of Dermatology, College of Medicine, Imam Mohammad Bin Saud University, Riyadh, Saudi Arabia.
Background: Necklines are a common complaint in patients as they are a sign of aging. Hyaluronic acid (HA) fillers are widely used to address volume loss and linear depressions. HA fillers are safe, effective, and versatile, but their use for necklines is not well-documented in the literature.
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