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Hazards constitute key quantities for analyzing, interpreting, and understanding time-to-event data. Hazards and corresponding effect measures, such as the hazard ratio from the Cox proportional hazards model, have a valid causal interpretation if the hazard function is considered as a function in time rather than hazards at specific time points. In this comment, we would like to add two points: (1) The hazard ratio is also a useful population-level estimand with a valid causal interpretation.
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