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Diabetic muscle infarction (DMI) is a rare complication of poorly controlled type 1 and type 2 diabetes seen mostly in those who have already experienced microvascular complications. Currently, the incidence and prevalence of DMI are difficult to conclude, and there is no clear algorithm or standard of care in managing this condition. Pathogenesis of the microangiopathy of DMI remains unclear. A major finding in this investigation of DMI emphasizes that, within 2-17 weeks, patients who initiate low-dose acetylsalicylic acid, bed rest, and close outpatient follow-up see significant size reduction of lower extremity mass and complete resolution of pain without being subjected to invasive muscle biopsy.
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http://dx.doi.org/10.1155/2021/5555051 | DOI Listing |
J Mol Histol
September 2025
Physiology Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran.
One of the most prevalent metabolic diseases in recent years, type 2 diabetes is now one of the top causes of death globally and a significant risk factor for cardiovascular diseases. Therefore, the goal of this study is to investigate the impact of HIIT exercises on the levels of specific proteins associated with mitochondrial biogenesis and apoptosis in the heart tissue of male Wistar rats with type 2 diabetes. Animals in diabetic groups were given a high-fat diet and an intraperitoneal injection of STZ to cause diabetes.
View Article and Find Full Text PDFNat Immunol
September 2025
Department of Pathology and Immunology, Washington University School of Medicine, St. Louis, MO, USA.
Crohn's disease pathology is modeled in TNF mice that overproduce tumor necrosis factor (TNF) to drive disease through TNF receptors. An alternative ligand for TNF receptors, soluble LTα, is produced by B cells, but has received scarce attention because LTα also partners with LTβ to generate membrane-tethered LTαβ that promotes tertiary lymphoid tissue-another feature of Crohn's disease. We hypothesized that B cell-derived LTαβ would critically affect ileitis in TNF mice.
View Article and Find Full Text PDFInt J Sports Physiol Perform
September 2025
Discipline of Exercise and Sport Science, School of Health Sciences, Faculty of Medicine and Health, University of Sydney, Camperdown, NSW, Australia.
Purpose: This study examined the effects of cluster sets (CS) versus traditional sets (TRAD) on performance and perceptual responses during pneumatic chest press (CP) and leg press (LP). Exercise-specific differences and the influence of sex and strength were also explored.
Methods: Forty-seven recreationally resistance-trained young adults (23 male and 24 female) performed CP and LP at 70% 1-repetition maximum in either CS (4 × [2 × 5], 30-s intraset rest, 150 s between sets) or TRAD (4 × 10, 180-s rest between sets) in randomized order.
J Craniofac Surg
September 2025
Department of Surgery, Cumming School of Medicine, University of Calgary, Calgary, Alberta.
Purpose: To demonstrate the use of negative pressure wound therapy (NPWT) and other reconstructive techniques in the reconstruction of large tissue defects resulting from periocular necrotizing fasciitis (NF).
Methods: Description of technique with 3 illustrative cases and accompanying photographic montage.
Results: Technique: Debridement successfully spared post-septal tissues and the lid margin in all cases.
Adv Sci (Weinh)
September 2025
Department of Bioengineering, Yildiz Technical University, Istanbul, 34722, Turkey.
Conductive nanocomposite hydrogels (CNHs) represent a promising tool in neural tissue engineering, offering tailored electroactive microenvironments to address the complex challenges of neural repair. This systematic scoping review, conducted in accordance with PRISMA-ScR guidelines, synthesizes recent advancements in CNH design, functionality, and therapeutic efficacy for central and peripheral nervous system (CNS and PNS) applications. The analysis of 125 studies reveals a growing emphasis on multifunctional materials, with carbon-based nanomaterials (CNTs, graphene derivatives; 36.
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