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Connected health is expected to introduce an improvement in providing healthcare and doctor-patient communication while at the same time reducing cost. Connected health would introduce an even more significant gap between healthcare quality for urban areas with physical proximity and better communication to providers and the portion of rural areas with numerous connectivity issues. We identify these challenges using user scenarios and propose LoRa based architecture for addressing these challenges. We focus on the energy management of battery-powered, affordable IoT devices for long-term operation, providing important information about the care receivers' well-being. Using an external ultra-low-power timer, we extended the battery life in the order of tens of times, compared to relying on low power modes of the microcontroller.
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http://dx.doi.org/10.3390/ijerph18147660 | DOI Listing |
J Invest Dermatol
September 2025
Department of Microbiology and Immunology, University of Maryland School of Medicine, Baltimore, MD, USA. Electronic address:
Wound healing has been extensively studied through the lens of inflammatory disorders and cancer, but limited attention has been given to hematophagy and arthropod-borne diseases. Hematophagous ectoparasites, including ticks, subvert the wound healing response to maintain prolonged attachment and facilitate blood-feeding. Here, we unveil a strategy by which extracellular vesicles (EVs) ensure blood-feeding and arthropod survival in three medically relevant tick species.
View Article and Find Full Text PDFActa Psychol (Amst)
September 2025
Wannan Medical College, Wuhu, Anhui, China. Electronic address:
Background: Mental health issues among middle school students are closely associated with life events and childhood trauma experiences. However, the interactive pathways among these three factors remain unclear. Based on network analysis, this study constructs a network model to identify core nodes (high-intensity symptoms) and bridge nodes (cross-group associated symptoms), aiming to reveal their interaction mechanisms and provide a foundation for targeted interventions in adolescent mental health.
View Article and Find Full Text PDFInt J Biol Macromol
September 2025
Jiangsu Collaborative Innovation Center of Chinese Medicinal Resources Industrialization, National and Local Collaborative Engineering Center of Chinese Medicinal Resources Industrialization and Formulae Innovative Medicine, Jiangsu Provincial Key Laboratory of Functional Substances in Traditional C
The immune system is the ultimate defense against diseases and its dysregulated homeostasis greatly threatens human health. Natural polysaccharides have a variety of biological activities and show promising applications in immunomodulation. In this study, we characterized the structure of the polysaccharide IRPS-TE-3 from Isatidis Radix using morphological analysis, molecular weight analysis, monosaccharide composition analysis, methylation analysis and nuclear magnetic resonance spectroscopy.
View Article and Find Full Text PDFAdv Nutr
September 2025
Department of Drug Discovery and Biomedical Sciences, College of Pharmacy, University of South Carolina, Columbia, 715 Sumter Street, CLS 513C, SC 29208, USA.
Human activities contribute to large shifts in the global climate, with far-reaching impacts on ecosystems, societies, and human health. Modern food systems-designed to produce convenience foods that tend to have high inflammatory potential-exacerbate environmental degradation and shape the interwoven challenges of climate, nutrition, and health. Over the past three decades, extreme weather has worsened and poor diets have led to more inflammation-related health problems-two parallel trends that are exposing system-wide weaknesses and harming global health.
View Article and Find Full Text PDFEcotoxicol Environ Saf
September 2025
Instititue of International Rivers and Eco-security, Yunnan Key Laboratory of Eco-security, Yunnan University, Kunming 650091, China.
Freshwater lakes are increasingly subject to simultaneous nutrient enrichment and antibiotic pollution, yet the joint effects of these stressors on microbial network structure remain poorly characterized. This study examined the combined effects of nutrients and antibiotics on bacterial communities across eight bays in Erhai Lake, which were classified into high-, moderate-, and low-pollution zones. High-pollution bays (Haichao, Dongsha, and Shuanglang) recorded the region's highest nutrient concentrations, with chemical oxygen demand reaching 33.
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