Volume control: Turning the dial on regulatory T cells.

Cell

Department of Immunology, University of Pittsburgh School of Medicine, University of Pittsburgh, Pittsburgh, PA, USA; Center for Systems Immunology, University of Pittsburgh, Pittsburgh, PA, USA. Electronic address:

Published: July 2021


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Article Abstract

Treg-mediated immunosuppression must be tightly regulated to support immunity while limiting tissue damage. In this issue of Cell, Wong et al. and Marangoni et al. use high-resolution imaging to define feedback circuits that quantitatively control local Treg expansion and function.

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http://dx.doi.org/10.1016/j.cell.2021.06.015DOI Listing

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