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The High Energy Physics (HEP) experiments, such as those at the Large Hadron Collider (LHC), traditionally consume large amounts of CPU cycles for detector simulations and data analysis, but rarely use compute accelerators such as GPUs. As the LHC is upgraded to allow for higher luminosity, resulting in much higher data rates, purely relying on CPUs may not provide enough computing power to support the simulation and data analysis needs. As a proof of concept, we investigate the feasibility of porting a HEP parameterized calorimeter simulation code to GPUs. We have chosen to use FastCaloSim, the ATLAS fast parametrized calorimeter simulation. While FastCaloSim is sufficiently fast such that it does not impose a bottleneck in detector simulations overall, significant speed-ups in the processing of large samples can be achieved from GPU parallelization at both the particle (intra-event) and event levels; this is especially beneficial in conditions expected at the high-luminosity LHC, where extremely high per-event particle multiplicities will result from the many simultaneous proton-proton collisions. We report our experience with porting FastCaloSim to NVIDIA GPUs using CUDA. A preliminary Kokkos implementation of FastCaloSim for portability to other parallel architectures is also described.
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http://dx.doi.org/10.3389/fdata.2021.665783 | DOI Listing |
Sensors (Basel)
August 2025
Institute of Space Science, Subsidiary of INFLPR, 409 Atomistilor Street, 077125 Magurele, Ilfov, Romania.
We present a Geant4-based simulation study of the electromagnetic sampling calorimeter (ECAL) foreseen in the LUXE experiment. The ECAL will enable precise measurement of the number and energy spectrum of positrons and electrons. The electromagnetic shower response, energy resolution, and linearity-properties that are essential for physics research-are studied.
View Article and Find Full Text PDFnpj Quantum Inf
July 2025
TRIUMF, Vancouver, BC V6T 2A3 Canada.
Particle collisions at accelerators like the Large Hadron Collider (LHC), recorded by experiments such as ATLAS and CMS, enable precise standard model measurements and searches for new phenomena. Simulating these collisions significantly influences experiment design and analysis but incurs immense computational costs, projected at millions of CPU-years annually during the high luminosity LHC (HL-LHC) phase. Currently, simulating a single event with Geant4 consumes around 1000 CPU seconds, with calorimeter simulations especially demanding.
View Article and Find Full Text PDFInt J Biol Macromol
June 2025
Key Laboratory of Agro-products Processing Technology, Jilin Provincial Department of Education, Changchun University, 6543 Weixing Road, Changchun 130022, Jilin Province, China. Electronic address:
A ternary conjugate ((EGCG-SPI)-EPS) formed by soybean protein isolate (SPI) with (-)-epigallocatechin gallate (EGCG) and exopolysaccharides (EPS) derived from Lactiplantibacillus plantarum A114 were prepared. The structure characteristic of (EGCG-SPI)-EPS were investigated by fluorescence or ultraviolet spectroscopy, Fourier transform infrared (FTIR), scanning electron microscopy (SEM) and differential scanning calorimeter (DSC), the results showed that covalent binding with EGCG and EPS resulted in structural alterations of SPI, characterized by fluorescence quenching, changes of secondary structure, an increase in UV ultraviolet absorption and thermal stability. SDS-PAGE result indicated that compared to native SPI, the molecular mass of (EGCG-SPI)-EPS was increased.
View Article and Find Full Text PDFBiochem Biophys Res Commun
July 2025
Key Laboratory of Industrial Biotechnology of Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China. Electronic address:
In recent years, monoclonal antibody drugs have dominated the bio-pharmaceutical market because of their high specificity and low adverse reactions. Antibody purification has always occupied most of the cost of antibody drug production. Protein A affinity chromatogra phy, as the most commonly used antibody purification method, has been explored to improve its service life and reduce the cost of purification.
View Article and Find Full Text PDFACS Nano
May 2025
Department of Mechanical Engineering, Carnegie Mellon University, 5000 Forbes Ave, Pittsburgh, Pennsylvania 15213, United States.
Anisotropic thermal transport was measured in imine-linked two-dimensional polymer (2DP) films that were prepared by interfacial polymerization. Measurements of both in-plane () and cross-plane () thermal conductivities relied on preparing free-standing 2DP films that were readily transferred for different measurement configurations. We polymerized two 2DP (Per-PDA and TAPPy-PDA) films at a liquid-liquid interface.
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