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http://dx.doi.org/10.1097/CM9.0000000000001570 | DOI Listing |
Adv Med Sci
September 2025
Department of Biology, Lund University, Lund, Sweden.
Purpose: Ovarian cancer ranks as a gynecological malignancy with poor prognosis, specifically if detected late. Primary treatment includes cytoreductive surgery and adjuvant chemotherapy with curative intent. Local anesthetics (LA) administered in the perioperative period may potentially impact patient outcome by several mechanisms.
View Article and Find Full Text PDFJ Agric Food Chem
September 2025
College of Food Science and Engineering, Northwest A&F University, Yangling, Shaanxi 712100, China.
In the search for novel succinate dehydrogenase inhibitors (SDHIs) fungicides for managing rice sheath blight (RSB) and sclerotinia stem rot (SSR), 28 pyrazole-4-carboxamides incorporating stilbene or diphenylacetylene scaffolds were synthesized and evaluated for antifungal activities. The results showed that compound exhibited the most promising antifungal efficacy against and with EC (half maximal effective concentration) values of 0.004 and 0.
View Article and Find Full Text PDFPest Manag Sci
September 2025
Department of Plant Protection, College of Plant Science, Jilin University, Changchun, China.
Background: Southern corn leaf blight (SCLB), caused by Cochliobolus heterostrophus, is a major disease that severely affects maize production globally, especially in tropical and subtropical regions. Conventional control strategies, such as chemical fungicides and resistant cultivars, are limited due to environmental and health concerns.
Results: This study explores Bacillus velezensis JLU-55 as a potential biological control agent against C.
Gastric Cancer
September 2025
Department of Gastroenterological Surgery, The University of Osaka Graduate School of Medicine, 2-2, Yamadaoka, Suita, Osaka, 565-0871, Japan.
Background: The tyrosine kinase inhibitor (TKI) imatinib targets KIT and PDGFRA, offering significant therapeutic benefits in advanced gastrointestinal stromal tumors (GISTs). However, the high rate of recurrence following treatment discontinuation suggests that drug-tolerant persister cells (DTPs) may contribute to therapy resistance. Elucidating the mechanisms underlying DTP survival is critical for the development of curative strategies.
View Article and Find Full Text PDFPestic Biochem Physiol
November 2025
College of Forestry, East China Woody Fragrance and Flavor Engineering Research Center of National Forestry and Grassland Administration; Jiangxi Provincial Key Laboratory of Improved Variety Breeding and Efficient Utilization of Native Tree Species and College of Agronomy, Key Laboratory of Crop Ph
Rhizoctonia solani (R. solani) is a phytopathogen that extensively affects crops, leading to plant diseases and reducing crop yields, which jeopardizes food security. β-pinene is a major component of turpentine oil and serves as a lead compound for developing new fungicides.
View Article and Find Full Text PDF