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Aim: We aimed to compare the functional results of two different vesicourethral anastomosis (VUA) techniques used in open retropubic radical prostatectomy.
Methods: A total of 476 patients including the first group with four-focus VUA at 12-, 3-, 6-, and 9-o'clock positions (n = 288) and the second group with six-focus VUA at 12-, 2-, 4-, 6-, 8-, and 10-o'clock (n = 188) were included in the study. Perioperative data, erectile function, and continence status over a 12-month period were compared.
Results: Demographic and perioperative data were similar between two groups. The number of patients with VUA stricture in the first group was significantly higher those in the second group (5.1% vs 3.2%, P = .017). The mean time to stricture development was also shorter in the first group (48.9 vs 74.3 days, P = .002). The number of continent patients at the 6th and 12th months were higher in the second group (79.3% vs 62.8%, P < .001; 92.4% vs 81.3%, P = .032, respectively). There was no significant difference between two groups in terms of the number of potent patients (P = .194 for 6 months and P = .351 for 12 months).
Conclusions: Better continence results can be provided with the six-focus VUA technique compared with the four-focus technique. The number of anastomotic sutures in VUA may affect functional results and can be a determinative factor for surgeons who focus on functional results as well as oncological results.
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http://dx.doi.org/10.1111/ijcp.14460 | DOI Listing |
Cleft Palate Craniofac J
September 2025
Otorhinolaryngology-Head and Neck Surgery Department, Faculty of Medicine, Zagazig University, Zagazig, Egypt.
ObjectiveTo compare between L pharyngeal flap alone and combined L pharyngeal flap with phenytoin for repair of palatal fistula and velopharyngeal insufficiency (VPI).MethodsTwenty patients with soft palate fistula and persistent VPI who were divided into two groups. In the first group, superiorly based L pharyngeal flap was harvested from the oropharynx and inserted into the soft palate to close the fistula after fistula trimming.
View Article and Find Full Text PDFClin Orthop Relat Res
September 2025
Leni & Peter W. May Department of Orthopaedic Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA.
Background: Peripheral nerve injury commonly results in pain and long-term disability for patients. Recovery after in-continuity stretch or crush injury remains inherently unpredictable. However, surgical intervention yields the most favorable outcomes when performed shortly after injury.
View Article and Find Full Text PDFAnn Surg Oncol
September 2025
Department of Hepatobiliary Surgery, Eastern Hepatobiliary Surgery Hospital, Naval Medical University, Shanghai, China.
Background: Postoperative late recurrence (POLAR) after 2 years from the date of surgical resection of hepatocellular carcinoma (HCC) represents a unique surveillance and management challenge. Despite identified risk factors, individualized prediction tools to guide personalized surveillance strategies for recurrence remain scarce. The current study sought to develop a predictive model for late recurrence among patients undergoing HCC resection.
View Article and Find Full Text PDFChilds Nerv Syst
September 2025
Department of Orthopedics, The Third Affiliated Hospital of Zhengzhou University, Zhengzhou, China.
Objective: To analyze the filum terminale (FT) of children with tethered cord syndrome (TCS) and aborted fetuses without neurological disorders in order to investigate the expression of significantly differentially expressed proteins in the FT under both pathological and physiological conditions.
Methods: According to the inclusion and exclusion criteria, 35 FT samples were selected, and the samples were subjected to immunohistochemistry and H&E staining. The data were analyzed using one-way analysis of variance, and P < 0.
FASEB J
September 2025
Department of Plastic Surgery and Burn, Third XiangYa Hospital, Central South University, Changsha, Hunan, China.
Defective wounds pose health risks, and treatment is challenging. Umbilical cord-derived mesenchymal stem cells (UCMSCs) show promise for healing. Primary UCMSCs were isolated and extracted in vitro, and the proliferation and differentiation characteristics were detected by flow cytometry and trilineage differentiation, and a 3D spherical cell culture was performed.
View Article and Find Full Text PDF