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Article Abstract
() is a regulator of multiple environmental stress responses required for stress acclimation. We analyzed co-regulated genes and identified 43 genes strongly co-regulated with during multiple stresses. Motif enrichment analysis revealed an over-representation of the site II element (SIIE) in the promoters of these genes. In a yeast 1-hybrid screen with the SIIE, we identified the closely related R2R3-MYB transcription factors TT2 and MYB5. We found overexpression of or rendered plants heat stress tolerant. In contrast, , , and loss of function mutants showed heat stress hypersensitivity. Transient expression assays confirmed that MYB5 and TT2 can regulate the promoter together with the other members of the MBW complex, TT8 and TRANSPARENT TESTA GLABRA 1 (TTG1) and that the SIIE was involved in this regulation. Transcriptomic analysis revealed that target promoters were enriched in SIIE. Overall, we report a new function of TT2 and MYB5 in stress resistance and a role in SIIE-mediated regulation.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC8156827 | PMC |
| http://dx.doi.org/10.3390/genes12050746 | DOI Listing |
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