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Residual intra-peritoneal gas may be associated with post-laparoscopic shoulder pain (PLSP), which is a frequently and disturbance compliant after surgery. Herein, we aimed to examine whether expiring residual gas via a surgical drain reduces the frequency and intensity of PLSP in the first day after laparoscopic cholecystectomy. 448 participants were enrolled in this prospective cohort study. The incidence and severity of PLSP after surgery were recorded. Of these, the cumulative incidence of PLSP in the drain group was lower particularly at the 12th postoperative hour (18.3% vs. 27.6%; P = 0.022), 24th postoperative hour (28.8% vs. 38.1%; P = 0.039), and throughout the first postoperative day (P = 0.035). The drain group had less severe PLSP (crude Odds ratio, 0.66; P = .036). After adjustment using inverse probability of treatment weighting, the drain group also had a significant lower PLSP incidence (adjusted hazard ratio = 0.61, P < 0.001), and less severe PLSP (adjusted odds ratio = 0.56, P < 0.001). In conclusion, the maneuver about passive force to expel residual gas, surgical drain use, contributes to reduce the incidence and severity of PLSP, suggesting that to minimize residual gas at the end of surgery is useful to attenuate PLSP.
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http://dx.doi.org/10.1038/s41598-021-85714-4 | DOI Listing |
Anal Chem
September 2025
Department of Radiotherapy, The First Affiliated Hospital of Soochow University, Suzhou, Jiangsu 215123, People's Republic of China.
Radiation therapy (RT) plays important roles in cancer treatment, and the efficacy of RT depends on the abscopal effect, which results in the regression of distant and untreated tumors through localized irradiation of a single tumor lesion. This effect is mediated by effector tumor antigen-specific T cells (ETASTs) activated by RT. Monitoring the radiation-induced changes in ETASTs can be used to predict the abscopal effect.
View Article and Find Full Text PDFJSLS
September 2025
Department of General Surgery, University of Health Sciences Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey. (Drs. Agca, Tasdelen, and Memisoglu).
Objective: In this study, we aimed to investigate the effectiveness of preperitoneal closed suction drainage in reducing postoperative complications in total extraperitoneal (TEP) repair inguinal hernia repair.
Methods: Between May 2021 and February 2023, 125 patients aged 18-80 years who were admitted to our hospital with primary unilateral (PM2, PM3 and PL2, PL3) inguinal hernia were included in preperitoneal drainage (group 1, n = 45) and no drainage groups (group 2, n = 80). Hematoma and seroma size, early postoperative bleeding, postoperative hospital stay, pain score and recurrence were recorded on the 6th day and 3rd month after surgery.
Am J Case Rep
September 2025
Department of Pediatrics, Southwest Healthcare Medical Education Consortium, Temecula, CA, USA.
BACKGROUND Morel-Lavallee lesions (MLLs) are uncommon, closed soft-tissue degloving injuries caused by high-energy trauma that are often missed due to their rarity and delayed presentation, resulting in serious complications. MLLs are particularly missed and underreported in pediatric and adolescent patients. We describe the case of an adolescent MLL occurring in an atypical lesion site at the calf to increase awareness of this diagnosis and associated presentation in this patient group, which can differ from adult presentation and contribute to diagnostic uncertainty that consequently impacts clinical decision-making.
View Article and Find Full Text PDFWorld Neurosurg
September 2025
Department of Neurosurgery, St. Marianna University School of Medicine, Kawasaki, Japan. Electronic address:
Although subdural drain (SDD) placement reduces recurrence after burr-hole surgery for chronic subdural hematoma (CSDH), complications have led our institution to discontinue its routine use. During the first year following this change, the recurrence rate was 14.6%, comparable to the recurrence rate observed prior to discontinuation.
View Article and Find Full Text PDFEur Spine J
September 2025
Department of Orthopedic Surgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
Purpose: Intraoperative bleeding remains a major challenge in lumbar spine surgery, with conventional assessment methods lacking standardization. The Validated Intraoperative Bleeding Severity Scale (VIBe) is a structured five-grade tool developed to objectively assess bleeding severity across surgical fields. This study evaluated the clinical utility of VIBe in lumbar spinal fusion by comparing it with conventional bleeding metrics across various hemostatic strategies, including hypotensive anesthesia and local hemostatic agent use.
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