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Purpose: To describe the key clinical, imaging, and arthroscopic characteristics of anchor arthropathy after arthroscopic shoulder stabilization procedures and, secondarily, to define risk factors for the development of anchor-induced arthropathy.
Methods: A total of 23 patients who underwent revision arthroscopic shoulder surgery and were diagnosed with glenohumeral arthropathy were retrospectively identified from prospectively collected data registries between January 2000 and May 2018. Data included initial diagnosis and index procedure performed, presenting arthropathy symptoms including duration, and examination findings before revision surgery. Pre-revision imaging was used to assess presence of glenohumeral osteoarthritis and chondromalacia, anchors/sutures, loose bodies, and labral pathology. The same parameters were recorded intraoperatively during revision surgery. Descriptive statistics were performed for demographic data and means with standard deviations were calculated for continuous data. A McNemar-Bowker test was used to analyze marginal homogeneity between preoperative imaging and intraoperative findings.
Results: Mean age at presentation was 33.4 ± 11.7 years (range 16-59, 17 male patients; 6 female patients). More than one half (13/23) developed symptoms within 10 months after index arthroscopic procedure (mean 32.2 ± 59.9 months, range <1 to 165.2 months) with 87% presenting with pain and 100% presenting with loss of motion on examination. Plain radiographs demonstrated humeral osteoarthritis in 57% (13/23) of patients, magnetic resonance imaging (MRI) revealed recurrent labral pathology in 19 of 23 (83%) patients, potential proud implants in 12 of 23 (52%), and loose bodies in 12 of 23 (52%). Intraoperatively, all had evidence of osteoarthritis; 22 of 23 (96%) had prominent implants. Humeral head chondromalacia was present in 21 of 23 patients (91%), the majority of which was linear stripe wear, and 6 of 23 (26%) had severe global glenohumeral osteoarthritis. Statistical analysis revealed a 54.5% (95% confidence interval 0.327-0.749) sensitivity of MRI identification of proud implants with a specificity of 100% (95% confidence interval 0.055-1). The ability of MRI to accurately assess chondromalacia of the humeral head (P = .342) or glenoid (P = .685) was not statistically significant.
Conclusions: Anchor arthropathy is characterized by symptoms of pain and stiffness on examination and in many cases develops early after stabilization surgery (<10 months). Implants were implicated in the majority of cases of humeral head chondromalacia. MRI scans may produce false-negative identification of proud implants and can be a poor predictor of the severity of chondromalacia and intra-articular pathology; thus, a high index of clinical suspicion is necessary in patients with motion loss and pain postoperatively.
Level Of Evidence: Level IV, case series.
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http://dx.doi.org/10.1016/j.arthro.2021.05.016 | DOI Listing |
Adv Healthc Mater
September 2025
State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou Veterinary Research Institute, Chinese Academy of Agricultural Sciences, Lanzhou, 730000, P. R. China.
Diabetic chronic wounds, driven by hyperglycemia-induced oxidative stress and multidrug-resistant bacterial infections, represent a highly challenging clinical issue. Existing therapies fall short in addressing the dual challenges of bacterial resistance and dysregulated wound microenvironments. Although metal-organic framework (MOF)-based nanozymes hold potential for catalytic antibacterial therapy, their clinical application is limited by insufficient active site exposure, structural instability of amorphous MOFs (aMOFs), and dependence on toxic exogenous HO.
View Article and Find Full Text PDFJBJS Case Connect
July 2025
Nemours Children's Health, Wilmington, Delaware.
Case: A 14-year-old adolescent girl with osteogenesis imperfecta presented with bilateral patellar instability. Examination showed subluxation (confirmed on imaging) with flexion >60° (left). Surgical treatment consisted of lateral retinacular lengthening, quadriceps realignment and lengthening, and medial patellofemoral ligament (MPFL) reconstruction with semitendinosus allograft using an all-suture anchor for femoral fixation and a basket-weave technique to secure the graft to the anterior patellar periosteum.
View Article and Find Full Text PDFAm J Sports Med
September 2025
Department of Orthopaedics and Trauma Surgery, Musculoskeletal University Center Munich, (MUM), University Hospital, LMU Munich, Munich, Bavaria, Germany.
Background: Despite studies on syndesmotic and deltoid ligament (DL) repair, the biomechanical role of (partial or full) ligament repair and bracing in unstable ankles to regain rotational stability remains unclear.
Purpose: To determine the ability of surgical intervention on syndesmosis and SLs with suture repair and ligament bracing to restore intact external rotation ankle stability.
Study Design: Controlled laboratory study.
Int J Mol Sci
August 2025
IRCCS Humanitas Research Hospital, Via Manzoni 56, 20089 Rozzano, Milan, Italy.
Autologous therapies are currently being studied to determine if they can modulate the course of knee osteoarthritis symptoms and/or disease progression. One potential therapeutic target is the polarization of pro-inflammatory M1 macrophages to pro-healing M2 macrophages. The autologous therapy, Autologous Protein Solution (APS), was incubated with donor-matched human peripheral-derived macrophages for 10 days.
View Article and Find Full Text PDFAnn Med Surg (Lond)
August 2025
Department of Rheumatology, Jefferson Einstein Philadelphia Hospital (Einstein Medical Center Pennsylvania), Philadelphia, Pennsylvania, USA.
Introduction And Importance: Rheumatoid arthritis (RA) presents with extra-articular manifestations in 15-25% of cases. Intra-osseous rheumatoid nodules occur in <1% of patients and mimic metastatic disease on imaging. When extra-articular features precede joint symptoms, diagnostic delays are common.
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