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The piezoelectric polymer PVDF and its copolymers have a long history as transducer materials for medical and biological applications. An efficient use of these polymers can potentially both lower the production cost and offer an environment-friendly alternative for medical transducers which today is dominated by piezoelectric ceramics containing lead. The main goal of the current work has been to compare the image quality of a low-cost in-house transducers made from the copolymer P(VDF-TrFE) to a commercial PVDF transducer. Several test objects were explored with the transducers used in a scanning acoustic microscope, including a human articular cartilage sample, a coin surface, and an etched metal film with fine line structures. To evaluate the image quality, C- and B-scan images were obtained from the recorded time series, and compared in terms of resolution, SNR, point-spread function, and depth imaging capability. The investigation is believed to provide useful information about both the strengths and limitations of low-cost polymer transducers.
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http://dx.doi.org/10.3390/polym13091462 | DOI Listing |
JAMA
September 2025
Division of Surgery and Interventional Science, UCL, London, United Kingdom.
Importance: Multiparametric magnetic resonance imaging (MRI), with or without prostate biopsy, has become the standard of care for diagnosing clinically significant prostate cancer. Resource capacity limits widespread adoption. Biparametric MRI, which omits the gadolinium contrast sequence, is a shorter and cheaper alternative offering time-saving capacity gains for health systems globally.
View Article and Find Full Text PDFJAMA
September 2025
Section of Urologic Oncology, Department of Urology, Michigan Medicine, Ann Arbor.
JAMA Cardiol
September 2025
Seymour, Paul and Gloria Milstein Division of Cardiology, Department of Medicine, Columbia University Irving Medical Center and New York-Presbyterian Hospital, New York, New York.
Importance: Transthyretin cardiac amyloidosis (ATTR-CA) is an underdiagnosed but treatable cause of heart failure (HF) in older individuals that occurs in the context of normal wild-type (ATTRwt-CA) or an abnormal inherited (ATTRv-CA) TTR gene variant. While the most common inherited TTR variant, V142I, occurs in 3% to 4% of self-identified Black Americans and is associated with excess morbidity and mortality, the prevalence of ATTR-CA in this at-risk population is unknown.
Objective: To define the prevalence of ATTR-CA and proportions attributable to ATTRwt-CA or ATTRv-CA among older Black and Caribbean Hispanic individuals with HF.
Phys Eng Sci Med
September 2025
Department of Physics, Faculty of Mathematics and Natural Sciences, Universitas Indonesia, Depok, 16424, Indonesia.
This study introduces a novel optimization framework for cranial three-dimensional rotational angiography (3DRA), combining the development of a brain equivalent in-house phantom with Figure of Merit (FOM) a quantitative evaluation method. The technical contribution involves the development of an in-house phantom constructed using iodine-infused epoxy and lycal resins, validated against clinical Hounsfield Units (HU). A customized head phantom was developed to simulate brain tissue and cranial vasculature for 3DRA optimization.
View Article and Find Full Text PDFActa Neurochir (Wien)
September 2025
Department of Neurosurgery, Medical University of Gdańsk, Gdańsk, Poland.
Purpose: Moyamoya disease (MMD) is a chronic cerebrovascular disorder characterized by progressive arterial stenosis and fragile collateral formation, elevating stroke risk. Revascularization is the standard treatment, yet up to 27% of patients experience ischemic events within a year due to bypass insufficiency. While digital subtraction angiography (DSA) remains the gold standard for assessing bypass function, it is invasive and time-consuming.
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