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This study analyses the gaps and issues in the production and distribution system of maize seed in Nepal. A total of 682 households were surveyed in 2017 by employing multistage random sampling with probability proportionate to size by representing different (tarai and hill) agro-ecological zones. Twelve focus group discussions (FGDs) and four key informant interviews (KII) were also carried out. Results showed that the old varieties like Rampur Composite and Manakamana-3 are still popular in the farmers' fields. The cost of seed production was about 48% and the profit of the producer was 18% of the consumer price. The share of wholesalers was 15% of the consumer price whereas it was 19% for retailer/agro-vet. The average total cost of production was found to be $1392/ha and gross income was $1925/ha with the 1.38 average B: C ratio; it is, therefore, a lucrative enterprise. Out of a total of 27 released varieties, only 12 varieties have been used in seed production. Results revealed that 83% of the farmers cultivate open-pollinated maize varieties whereas 17% of them cultivate hybrid maize varieties. Seventy-five per cent of seed was from a formal source. The maize productivity, hybrid maize area, and seed replacement were below the targets set in Nepals' National Seed Vision, a policy document of the government. Focus on the production of nucleus and breeder seed by Government research farms and use of these seeds by private seed companies and community seed producing groups to produce next generation foundation seeds are urgently required. Equally important is enabling private and community-based organizations to produce hybrid seeds of the crop.
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http://dx.doi.org/10.1016/j.heliyon.2021.e06775 | DOI Listing |
BMC Glob Public Health
September 2025
Connell School of Nursing, Boston College, Chestnut Hill, MA, USA.
Background: Sierra Leone has the world's third highest incidence of maternal mortality, with 443 deaths per 100,000 live births. Strengthening the country's midwifery workforce is essential to providing adequate maternal healthcare and reducing preventable perinatal mortality. In support of this goal, we developed and implemented a midwifery preceptor program (MPP) to train experienced midwives to effectively mentor new and student midwives.
View Article and Find Full Text PDFTheor Appl Genet
September 2025
State Key Laboratory of Vegetable Biobreeding, Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing, 100081, China.
Hybrid breeding based on male sterility requires the removal of male parents, which is time- and labor-intensive; however, the use of female sterile male parent can solve this problem. In the offspring of distant hybridization between Brassica oleracea and Brassica napus, we obtained a mutant, 5GH12-279, which not only fails to generate gynoecium (thereby causing female sterility) but also has serrated leaves that could be used as a phenotypic marker in seedling screening. Genetic analysis revealed that this trait was controlled by a single dominant gene.
View Article and Find Full Text PDFMol Psychiatry
September 2025
Center for Depression, Anxiety and Stress Research, McLean Hospital, Belmont, MA, USA.
Dysregulated dopaminergic signaling has been implicated in the pathophysiology of major depressive disorder (MDD) and childhood sexual abuse (CSA), but inconsistencies abound. In a multimodal PET-functional MRI study, harnessing the highly selective tracer [C]altropane, we investigated dopamine transporter availability (DAT) and resting-state functional connectivity (rsFC) within reward-related regions among 112 unmedicated individuals (MDD: n = 37, MDD/CSA: n = 18; CSA no MDD: n = 14; controls: n = 43). Striatal DAT and seed-based rsFC were assessed in the dorsal and ventral striatum and the ventral tegmental area.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
September 2025
Faculty of Environment and Resource Studies, Mahidol University, Salaya, Phutthamonthon, Nakhon Pathom, 73170, Thailand.
Soil washing with surfactants is a promising technique for remediating petroleum hydrocarbon-contaminated soils. This study evaluates a biosurfactant extracted from Eichhornia crassipes (water hyacinth), an abundant aquatic weed in Thailand, using ultrasound-assisted extraction for diesel-contaminated soil remediation. The biosurfactant extract (Extract WH) was characterized for its surface tension reduction, critical micelle concentration (CMC), emulsification capacity with diesel, and phytotoxicity.
View Article and Find Full Text PDFEMBO Rep
September 2025
Institute for Stem Cell Science and Regenerative Medicine (inStem), GKVK post, Bellary Road, Bangalore, Karnataka, 560065, India.
Immune cells are increasingly recognized as nutrient sensors; however, their developmental role in regulating growth under homeostasis or dietary stress remains elusive. Here, we show that Drosophila larval macrophages, in response to excessive dietary sugar (HSD), reprogram their metabolic state by activating glycolysis, thereby enhancing TCA-cycle flux, and increasing lipogenesis-while concurrently maintaining a lipolytic state. Although this immune-metabolic configuration correlates with growth retardation under HSD, our genetic analyses reveal that enhanced lipogenesis supports growth, whereas glycolysis and lipolysis are growth-inhibitory.
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