Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1136/bmj.n988 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Autophagy inhibition in LGALS9-overexpressing nasopharyngeal carcinoma unleashes immune response.
Autophagy
July 2025
Life Sciences Institute, University of Michigan, Ann Arbor, MI, USA.
When cells within our bodies begin to exhibit tumor-specific antigens, a specialized group of immune cells, known as immune effector cells, plays a crucial role in mounting both innate and adaptive immune responses. Cancer cells are notorious for developing strategies to hide from, suppress, and manipulate the immune system, collectively known as immune evasion. In the paper by Kam et al.
View Article and Find Full Text PDFA survey of pathogenic involvement in non-communicable human diseases.
Commun Med (Lond)
June 2025
Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
Background: Many relationships between pathogens and human disease are well-established. However, only a small fraction involve diseases considered non-communicable (NCDs). In this study, we sought to leverage the vast amount of newly available electronic health record data to identify potentially novel pathogen-NCD associations and find additional evidence supporting known associations.
View Article and Find Full Text PDFTrogocytosis: revealing new insights into parasite-host interactions.
Trends Parasitol
July 2025
Department of Parasitology, Zhongshan School of Medicine, Sun Yat-Sen University, Guangzhou 510080, PR China; Key Laboratory of Tropical Disease Control of the Ministry of Education, Sun Yat-sen University, Guangzhou 510080, PR China; Provincial Engineering Technology Research Center for Biological
Trogocytosis - a process whereby cells physically nibble and ingest membrane fragments and other components from neighboring cells - plays a critical role in host-parasite interactions by modulating parasite survival and host immune responses. This review explores trogocytosis in parasitic infections, revealing its dual roles: parasites use it for nutrient acquisition and immune evasion, whereas hosts use it for pathogen clearance. We analyze the molecular machinery driving this process, its impact on infection outcomes, and parallels in tumors/transplantation.
View Article and Find Full Text PDFA subtle pre-excitation playing hide and seek.
Indian Pacing Electrophysiol J
May 2025
Department of Cardiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India. Electronic address:
24 years female presented with recurrent palpitations for one year. Sinus ECG showed preexcitation pattern suggestive of a posteroseptal accessory pathway. During the electrophysiology study, atrioventricular reciprocating tachycardia was induced with an atrial extra stimulus.
View Article and Find Full Text PDFFecal microbiota transplants (FMT) of three distinct human communities to germ-free mice exacerbated inflammation and decreased lung function in their offspring.
mBio
May 2025
Comparative Enteric Diseases Laboratory, Michigan State University, East Lansing, Michigan, USA.
Unlabelled: Despite explosive rise in allergies, little is known about early life gut microbiota effects on postnatal respiratory function. We hypothesized that -dominant gut microbiota from eczemic infants increases Type 2 inflammation and decreases lung function in transplanted mice, while -dominant gut microbiota from non-eczemic infants is protective. Fecal microbiota transplants (FMT) from eczemic infants "Infant A" and non-eczemic infants "Infant B" were successfully transplanted into germ-free C57BL/6 mice, passing to offspring unchanged.
View Article and Find Full Text PDF