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Mechanical ventilation in recent years has benefited from the development of new techniques and interfaces. These developments allowed clinicians to offer increasingly personalised therapies with the combination of different complementary techniques for treating respiratory insufficiency in patients with neuromuscular diseases. The mouthpiece ventilation, intermittent abdominal pressure ventilator and the negative pressure ventilation can offer many patients alternative therapy options when ventilation is required for many hours a day. In this non-systematic review, we will highlight the use of alternative methods to non-invasive mechanical ventilation at positive pressure in neuromuscular patients, to ensure the optimal interface for each patient.
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http://dx.doi.org/10.36185/2532-1900-042 | DOI Listing |
J Hazard Mater
September 2025
Architectural Engineering Department, Pennsylvania State University, University Park, PA, USA. Electronic address:
Far-UVC systems and air cleaners are effective strategies for controlling airborne pathogen transmission, particularly in densely occupied spaces with insufficient ventilation, such as school classrooms. This study evaluates the disinfection performance and ozone (O) formation of different far-UVC systems and air cleaners in a standard-sized classroom using computational fluid dynamics (CFD) simulation. Results show that ceiling-mounted far-UVC systems reduce airborne pathogen exposure by up to 30 % more than upper-room and wall-mounted configurations, based on intake fractions and room-average concentrations.
View Article and Find Full Text PDFJ Crit Care
September 2025
Universidade do Oeste de Santa Catarina, Campus de Joaçaba, Brazil; Hospital Universitário Santa Terezinha, Joaçaba, Brazil. Electronic address:
Background: Timely extubation is essential in ICU patients, yet traditional predictors such as the rapid shallow breathing index (RSBI) have limited accuracy. Diaphragm and lung ultrasound offer promising, non-invasive alternatives for assessing extubation readiness.
Methods: We conducted a prospective observational study nested within a randomized trial in a university ICU.
J Med Ultrason (2001)
September 2025
Department of Emergency Medicine, Faculty of Medicine, Kindai University, Osaka, Japan.
Purpose: This study aimed to investigate muscle atrophy in critically ill patients using ultrasonography. We compared the rectus femoris (a major muscle of the lower limbs) with the sternocleidomastoid (an accessory respiratory muscle).
Methods: Thirty-four patients hospitalized at the Critical Care Medical Center of Kindai University Hospital between January 2022 and March 2023 were enrolled.
J Neurointerv Surg
September 2025
Shanxi Key Laboratory of Brain Disease Control, Department of Neurology, Shanxi Provincial People's Hospital, Taiyuan, Shanxi, China
Background: This study aims to develop an interpretable machine learning model using SHapley Additive exPlanations (SHAP) to predict favorable outcomes based on clinical, imaging, and angiographic data.
Methods: This study analyzed data from 184 patients with acute basilar artery occlusion (BAO) who underwent endovascular treatment (EVT) and completed a 90-day follow-up at Shanxi Provincial People's Hospital. A total of 68 medical variables were collected to develop predictive models using three machine learning algorithms: logistic regression (LR), support vector machine (SVM), and Light Gradient Boosting Machine (LightGBM).
BMJ Open
September 2025
Department of Neonatal Health Nursing, School of Nursing, College of Medicine and Health Sciences, and Specialized Hospital, University of Gondar, Gondar, Ethiopia.
Objective: To assess the incidence of delirium and its predictors among adult patients admitted to the intensive care units of comprehensive specialised hospitals in the Amhara region of northwest Ethiopia from 18 October 2024 to 20 February 2025.
Design: A multicentre prospective observational study was conducted.
Setting: Four comprehensive specialised hospitals in the Amhara region of northwest Ethiopia, from 18 October 2024 to 20 February 2025.