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Slow drift rate has become one of the most salient cognitive deficits among children with ADHD, and has repeatedly been found to explain slow, variable, and error-prone performance on tasks of executive functioning (EF). The present study applies the diffusion model to determine whether slow drift rate better predicts parent and teacher ratings of ADHD than standard EF metrics. 201 children aged 8-12 completed two tests of speeded decision-making analyzed with the diffusion model and two traditionally scored tests of EF. Latent EF and drift rate factors each independently predicted the general ADHD factor in a bifactor model of ADHD, with poor EF and slow drift rate associated with greater ADHD symptomology. When both EF and drift rate were entered into the model, slow drift rate (but not EF) continued to predict elevated symptomology. These findings suggest that using drift rate to index task performance improves upon conventional approaches to measuring and conceptualizing cognitive dysfunction in ADHD. Implications for future cognitive research in ADHD are discussed.
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http://dx.doi.org/10.1080/09297049.2021.1902490 | DOI Listing |
Horm Metab Res
September 2025
Endocrinology, Metabolic Center for Wellness, Oviedo, United States.
Thyroid hormones (TH), primarily triiodothyronine (T3) and thyroxine (T4), are critical regulators of metabolic rate, mitochondrial function, and cellular repair mechanisms. Emerging evidence suggests that thyroid status may significantly influence aging trajectories and longevity through modulation of key cellular pathways. Objective: This review explores the role of thyroid hormones in aging biology, with a focus on their interaction with longevity-associated signaling pathways and the hallmarks of aging.
View Article and Find Full Text PDFJ Neurosurg Anesthesiol
October 2025
Department of Anesthesia and Perioperative Medicine, Western University.
Introduction: Current commercial cerebral oximeters only monitor the frontal lobes, however, some cerebrovascular territories may experience ischemia while others remain well perfused. This pilot study used a novel, high-density, dual-wavelength, time-resolved functional cerebral oximeter (Kernel Flow) with 2000 channels to assess the regional differences of cerebral oxygenation (StO2) in response to hypotension across different vascular territories during shoulder surgery in the beach chair position.
Methods: Twenty-seven adult patients were monitored, recording blood pressure, heart rate, regional cerebral oxygen saturation, and other vital parameters.
J Exerc Rehabil
August 2025
Department of Maritime Engineering, Faculty of International Maritime Studies, Kasetsart University, Chonburi, Thailand.
Obesity is associated with reduced exercise tolerance, yet the physiological mechanisms underlying this impairment remain unclear. This study examined whether oxygen uptake (V̇O) kinetics reflect autonomic regulation during prolonged moderate-intensity exercise in normal-weight and obese males. This cross-sectional study included nine normal-weight and nine obese males (aged 20-22) who performed 30 min of constant-load cycling at 70% of ventilatory threshold to assess V̇O kinetics and heart rate variability (HRV) responses.
View Article and Find Full Text PDFJ Contam Hydrol
September 2025
School of Marine Sciences, Sun Yat-sen University, 135 Xin'gang RD.W., Guangzhou 510275, China; Southern Marine Science and Engineering Guangdong Laboratory (Zhuhai), Zhuhai 519080, China. Electronic address:
We systematically investigated DNEs throughout imbibition processes, specifically evaluating: (1) the temporal correspondence between DNE development and changes in water saturation/capillary pressure, and (2) the dominant factors governing DNE magnitude during imbibition. The signal drift during extended testing, and the gravitational effect on both the capillary pressure and water saturation were eliminated. The results indicate that, when water saturation was below a threshold value (∼0.
View Article and Find Full Text PDFPLoS Med
September 2025
Department of Orthopaedics, Tampere University Hospital, Tampere, Finland.
Background: The optimal management of distal radius fractures (DRFs) in older patients remains debatable. A knowledge gap exists concerning how to manage fractures with early malalignment during nonoperative treatment. We conducted a prospective, multicenter, and randomized controlled trial to compare nonoperative treatment to operative treatment with volar locking plating (VLP) in the management of primarily malaligned DRFs and DRFs that exhibit early malalignment during nonoperative treatment.
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