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The homogeneity of the magnetic field generated by a coil inside a magnetic shield is essential for many applications, such as ultra-low field nuclear magnetic resonance or spin precession experiments. In the course of upgrading the Berlin Magnetically Shielded Room (BMSR-2) with a new inserted Permalloy layer of side length 2.87 m, we designed a built-in coil consisting of four identical square windings attached to its inside walls. The spacings of the four windings were optimized using a recently developed semi-analytic model and finite element analysis. The result reveals a strong dependence of the field homogeneity on the asymmetric placement of the inner two windings and on the chosen material permeability value μ. However, our model calculations also show that these experimental variations can be counterbalanced by an adjustment of the inner winding positions in the millimeter range. Superconducting quantum interference device-based measurements yield for our implementation after fine adjustments of a single winding position a maximum field change of less than 10 pT for a total field of B = 2.3 µT within a 10 cm region along the coil axis, which is already better than the residual field of the upgraded BMSR-2.1 after degaussing. Measurements of free spin precession decay signals of polarized Xe129 nuclei show that the transverse relaxation time for the used cell is not limited by the inhomogeneity of the new built-in coil system.
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http://dx.doi.org/10.1063/5.0027848 | DOI Listing |
Nat Biomed Eng
July 2025
Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Charlestown, MA, USA.
Defining the connectome, the complete matrix of structural connections between the nervous system nodes, is a challenge for human systems neuroscience due to the range of scales that must be bridged. Here we report the design of the Connectome 2.0 human magnetic resonance imaging (MRI) scanner to perform connectomics at the mesoscopic and microscopic scales with strong gradients for in vivo human imaging.
View Article and Find Full Text PDFAnnu Int Conf IEEE Eng Med Biol Soc
July 2024
We propose a wireless data uplink and localization method for miniaturized sensor implants through magnetic resonance imaging (MRI). Local MRI signals are dynamically modulated by a micro-coil on an integrated circuit (IC). A proof-of-concept chip was designed and tested in a 3T scanner to demonstrate MR image modulation.
View Article and Find Full Text PDFMagn Reson Imaging
February 2025
Department of Radiology, Beijing Tsinghua Changgung Hospital, School of Clinical Medicine, Tsinghua University, Beijing 102218, China. Electronic address:
IEEE Trans Biomed Eng
July 2024
Objective: Implanted Cardioverter Defibrillators (ICDs) induce a large (100 parts per million) inhomogeneous magnetic field in the magnetic resonance imaging (MRI) scanner which cannot be corrected by the scanner's built-in shim coils, leading to significant image artifacts that can make portions of the heart unreadable. To compensate for the field inhomogeneity, an active shim coil capable of countering the field deviation in user-defined regions was designed that must be optimally placed at patient-specific locations. We aim to develop and evaluate an MR-safe robotic solution for automated shim coil positioning.
View Article and Find Full Text PDFJpn J Radiol
April 2024
Department of Advanced Nuclear Medicine Sciences, Institute of Quantum Medical Science, National Institutes for Quantum Science and Technology (QST), 4-9-1 Anagawa, Inage, Chiba, 263-8555, Japan.