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Objective: Tracheal stenosis can have a variety of presentations, severities, causes, and be a difficult condition to treat. Some patients demonstrate recurrent stenosis after multiple endoscopic treatments and are either poor candidates for open procedures or do not desire open surgery. We sought to evaluate low-dose postoperative external beam radiotherapy (EBRT) as a novel therapy for patients with recurrent tracheal stenosis refractory to endoscopic therapies.
Method: We performed a retrospective review of patients with recurrent tracheal stenosis who underwent EBRT in addition to endoscopic dilation. We compared the number of endoscopic procedures required in the 6 months before EBRT to the number required in the 6 months after EBRT.
Results: Six patients met criteria for inclusion in our study. The cause of stenosis was variable among the study population. In the 6 months leading up to EBRT, patients underwent an average 6.2 endoscopic procedures. This dropped to an average 1.9 procedures in the 6 months following EBRT ( < .001).
Conclusion: Herein, we show that low-dose postoperative external beam radiotherapy (EBRT), a novel therapy for patients with recurrent tracheal stenosis refractory to endoscopic therapies, is effective in decreasing the frequency of endoscopic dilations.
Level Of Evidence: 4.
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http://dx.doi.org/10.1177/0003489421995064 | DOI Listing |
Paediatr Anaesth
September 2025
Department of Anesthesiology & Pain Medicine, Nationwide Children's Hospital, Columbus, Ohio, USA.
Introduction: Endotracheal tube (ETT) cuff pressures that exceed 20-30 cmHO may lead to iatrogenic adverse effects such as cough, sore throat, and tracheal edema or more serious complications including tracheal stenosis, recurrent laryngeal nerve injury, and tracheal rupture. The current study evaluates a novel technique, titration of the ratio of expiratory to inspiratory tidal volumes (TV), to regulate intracuff pressure.
Methods: This prospective, cross-over trial measured intracuff pressure in a cohort of pediatric patients presenting for general anesthesia with an ETT.
Eur Radiol
September 2025
Department of Radiology, Children's Hospital of Chongqing Medical University, National Clinical Research Center for Child Health and Disorders, Ministry of Education Key Laboratory of Child Development and Disorders, Chongqing Key Laboratory of Structural Birth Defect and Reconstruction, Chongqing,
Objective: To develop a 1.5-T MR imaging protocol tailored for organic laryngotracheal stenosis (LTS) and to assess its performance in visualizing anatomy and pathologies.
Materials And Methods: Presurgical laryngotracheal 1.
J Pediatr Surg
September 2025
Hospital de Clínicas de Porto Alegre (HCPA), Rua Ramiro Barcelos, 2350, Santa Cecília, 90035-003, Porto Alegre, Rs, Brazil; Universidade Federal do Rio Grande do Sul (UFRGS), Rua Ramiro Barcelos, 2400, Santa Cecília, 90035-003, Porto Alegre, RS, Brazil.
Background: Obstructions of the tracheobronchial tree can result from various etiologies. Most cases of tracheal stenosis or tracheomalacia are associated with patient-specific anatomical and functional abnormalities, making treatment challenging. Despite progress in the development of tracheal support devices, the optimal or near-optimal stent design remains elusive.
View Article and Find Full Text PDFAirway stents provide symptomatic relief in malignant central airway stenosis, but carry the risk of migration, which may result in potentially lethal stent ingestion. A 22-year-old man underwent hybrid stent placement for tracheobronchial stenosis caused by an undiagnosed large mediastinal mass. Within 3 weeks after placement, following initial chemotherapy for provisionally diagnosed B-cell lymphoma, the stent migrated and was ingested.
View Article and Find Full Text PDFVestn Otorinolaringol
September 2025
Pirogov Russian National Research Medical University, Moscow, Russia.
The article presents a review of the literature, in which the possibilities of conservative therapy in the treatment of chronic scar stenosis of the larynx and cervical trachea are considered. Due to the high risk of restenosis of the larynx and cervical trachea lumen in the postoperative period, the problem under consideration remains topical. The authors have systematised modern literature data on the groups of used drugs, mechanisms of action and routes of delivery, advantages and disadvantages, and reviewed the experience of their use in otorhinolaryngology.
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