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http://dx.doi.org/10.1093/eurjpc/zwaa055 | DOI Listing |
Pol Merkur Lekarski
September 2025
I. HORBACHEVSKY TERNOPIL NATIONAL MEDICAL UNIVERSITY, TERNOPIL, UKRAINE.
Objective: Aim: To evaluate the state of oxidation processes and morphological changes in the heart of rats with chronic hypodynamia during the development of epinephrine heart damage (EHD)..
Patients And Methods: Materials and Methods: The study was performed on 144 white male Wistar rats.
Elife
September 2025
Department of Neuroscience, Washington University School of Medicine, St Louis, United States.
Peripheral sensory neurons regenerate their axons after injury to regain function, but this ability declines with age. The mechanisms behind this decline are not fully understood. While excessive production of endothelin 1 (ET-1), a potent vasoconstrictor, is linked to many diseases that increase with age, the role of ET-1 and its receptors in axon regeneration is unknown.
View Article and Find Full Text PDFJ Exp Anal Behav
September 2025
Faillace Department of Psychiatry and Behavioral Sciences, University of Texas Health Science Center at Houston, Houston, USA.
Polydrug abuse is the persistent self-administration of more than one reinforcing drug. The present study provided rhesus monkeys concurrent access to two drugs: 8% alcohol and solutions of either cocaine or methadone. The liquids were available under concurrent nonindependent fixed-ratio (FR) schedules across increasing and then decreasing ratio sizes.
View Article and Find Full Text PDFBrain Behav
September 2025
Faculty of Medicine, Department of Physiology, Hacettepe University, Ankara, Türkiye.
Purpose: The rapid onset of anxiolytic drugs without cognitive or motor impairments remains an unmet need. This study evaluated the acute anxiolytic effects of Salvia heldreichiana essential oil in rats, measuring anxiety-related behaviors, hippocampal levels of serotonin, noradrenaline, gamma-aminobutyric acid GABA, and serum cortisol.
Method: Forty-eight male Wistar albino rats were divided into two experiments.
Proc Natl Acad Sci U S A
September 2025
Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853.
Ovulation is an intricate process that is essential for reproductive success. In , ovulation increases after mating. This increase is initiated by the male seminal fluid protein ovulin and is executed by female pathways, including octopamine (OA) neuronal signaling.
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