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http://dx.doi.org/10.1002/art.41682 | DOI Listing |
Sci Rep
August 2025
Department of Nursing, School of Nursing and Midwifery, Shiraz University of Medical Sciences, Shiraz, Fars, Iran.
Intravenous catheter insertion is the most common procedure in the hospital setting and causes significant pain and anxiety for hospitalized children. This randomized controlled trial aimed to compare the effects of stress ball squeezing and pinwheel blowing on pain and anxiety levels during intravenous catheter insertion in hospitalized school-aged children. Ninety children aged 6-12 years admitted to the pediatric wards of Namazi Hospital in Shiraz, Iran, between May and September 2024, were randomly assigned to three groups: a stress ball group, a pinwheel group, and a control group.
View Article and Find Full Text PDFHealth Technol Assess
August 2025
Warwick Medical School, University of Warwick, Coventry, UK.
Background: Cardiovascular disease remains a leading cause of morbidity and mortality worldwide. This series of systematic reviews and meta-analyses synthesised evidence on the effectiveness, comparative effectiveness and cost-effectiveness of pharmacological and non-pharmacological interventions for primary cardiovascular disease prevention.
Methods: Five systematic reviews and meta-analyses were conducted using rigorous methods, including comprehensive searches, duplicate screening, risk-of-bias assessments and adherence to reporting guidelines.
Children (Basel)
June 2025
National Centre for Respiratory Pharmacoeconomics and Pharmacoepidemiology-CESFAR, 37124 Verona, Italy.
Bronchial asthma is a respiratory chronic disorder frequently affecting youth. It is characterized by a huge personal, familial, and societal impact. Biological and cellular studies in recent decades define asthma as a chronic inflammatory disease of the airways.
View Article and Find Full Text PDFClinics (Sao Paulo)
July 2025
General Surgery Department, Xuanwu Hospital, Beijing, China. Electronic address:
Objective: Based on the data in clinical studies, the authors explored the potential link between cancer immunotherapy and Neurological Adverse Events (NAEs), and established a clinical picture.
Methods: The authors searched PubMed, Embase, Cochrane Library, Web of Science databases, and ClinicalTrials.gov for Randomized Controlled Trials (RCTs) using PD-1/PD-L1 inhibitors for cancer until November 2023.
J Eat Disord
July 2025
James Cook University Hospital, Middlesbrough, UK.
Background: Males with eating disorders (EDs) are an underrepresented population whose symptomatology and treatment needs are poorly understood, having been overlooked in clinical research to date. The role of gastrointestinal disorders, such as gastroparesis, in the context of restrictive EDs is similarly under-explored. Making use of emerging evidence regarding conditions that co-occur with severe EDs to consider potential differential diagnoses in cases of complex and uncertain symptomatology can assist in providing more individualised and empathetic care, preventing avoidable outcomes, including death.
View Article and Find Full Text PDF