Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
The genus comprises species that cause nosocomial and community-acquired infections. A dataset was created to compile the sequence type (ST) and capsule type (K-locus) information predicted for 172 worldwide isolates of spp. whose complete genomes could be retrieved from the GenBank (NCBI) repository. The dataset also includes information related to one multidrug-resistant strain (B31) isolated from a patient who was admitted to an intensive care unit in the Northeast region of Brazil. This strain was phenotypically characterized and submitted to whole-genome sequencing and comparative genomics analysis as we recently reported [1]. The dataset also compiles information on Pathogenicity Islands (PIs), Resistance Islands (RIs) and Miscellaneous Islands (MIS) present in the genome of strain B31. The information provided here may support outbreak prevention policies and future epidemiological studies involving spp.
Download full-text PDF |
Source |
|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC7829145 | PMC |
| http://dx.doi.org/10.1016/j.dib.2021.106746 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Protective efficacy of mutant strains of as potential reservoir host-targeted biologics against Lyme disease.
bioRxiv
July 2025
South Texas Center for Emerging Infectious Diseases, Department of Molecular Microbiology and Immunology, The University of Texas at San Antonio San Antonio, TX-78249.
Lyme disease (LD), caused by (), is the most common vector-borne disease in the United States. Methods to control the transmission of to humans via ticks are critical for prevention and elimination of LD. Previously, we showed that deletion of Borrelia hostadaptation Regulator ( mutant) and replacement of 8 conserved residues in Carbon Storage Regulator A of (CsrA, 8S mutant) resulted in upregulation of several lipoproteins due to increased levels of RpoS.
View Article and Find Full Text PDFStrain-Specific Differences in Mouse Infectivity and Pathology.
Pathogens
April 2025
Centre for Oncology, Radiopharmaceuticals and Research, Biologic and Radiopharmaceutical Drugs Directorate, Health Products and Food Branch, Health Canada and World Health Organization Collaborating Center for Standardization and Evaluation of Biologicals, Ottawa, ON K1A 0K9, Canada.
Lyme disease (LD), caused by infection with the tick-borne bacteria, , is associated with a wide array of symptoms in human patients. Variations in clinical manifestations are thought to be influenced by genetic differences among strains. In this study, we evaluated the infectivity, tissue bacterial load, pathology, and immunogenicity of five strains of sensu stricto (297 Ah130, Bb16-54, B31-A3, Bb16-126, JD1) in female C3H/HeN mice at three infectious doses (10, 10, 10 spirochetes).
View Article and Find Full Text PDFA Lyme disease mRNA vaccine targeting OspA induces strong immune responses and prevents transmission in mice.
Mol Ther Nucleic Acids
June 2025
Institut Pasteur, Environnement et Risques Infectieux, Université Paris Cité, 75015 Paris, France.
Lyme borreliosis (LB), caused by sensu lato, is one of the most common tick-borne diseases in the northern hemisphere. Given its increasing global incidence, LB remains a major public health concern and the development of an effective vaccine is recognized as a key component of the overall disease prevention strategy. Here, we present results obtained with newly developed lipid nanoparticle-encapsulated mRNA vaccine candidates encoding the outer surface protein A (OspA) of sensu stricto (Bbss) serotype 1 (mRNA-OspA) with or without a secretion signal (SS) or a transmembrane domain.
View Article and Find Full Text PDFDevelopment and Utilization of Quantitative Detection for Probiotics Bacillus velezensis B31 with Potential Protection Against Tomato Fusarium Wilt.
Probiotics Antimicrob Proteins
March 2025
Plant Protection Institute, Hebei Academy of Agriculture and Forestry Sciences/Key Laboratory of Integrated Pest Management on Crops in Northern Region of North China, Ministry of Agriculture and Rural Affairs, People'S Republic of China/IPM Innovation Center of Hebei Province/International Science
The biocontrol efficacy of probiotics Bacillus velezensis B31 against fusarium wilt is contingent upon its successful colonization in the plant rhizosphere. This study aimed to develop a quantitative detection method for probiotics strain B31 and to monitor its rhizosphere dynamics. Utilizing comparative genomics, a specific gene in strain B31 was identified, which facilitated the design of precise primers and a Taqman probe.
View Article and Find Full Text PDFQuadriceps muscle injuries in athletes: a narrative review.
Br J Radiol
May 2025
Department of Musculoskeletal Radiology, The Royal Orthopaedic Hospital NHS Foundation Trust, Birmingham, B31 2AP, United Kingdom.
The quadriceps muscles are a large group of 4 muscles in the anterior compartment of the thigh, comprising the rectus femoris, vastus medialis, vastus intermedius, and vastus lateralis, which in combination act as the primary extensors of the knee joint. The rectus femoris is also responsible for hip joint flexion. Quadriceps muscle injuries are frequently encountered in sports and athletic activities and present a significant challenge in the realm of sports medicine, impacting athletes across various disciplines and levels of competition.
View Article and Find Full Text PDF