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Amputation surgery in pinniped rehabilitation centers is a feasible procedure when animals are presented with open fractures, osteomyelitis, and/or infectious arthritis of the flippers that appear to be refractory to medical treatment. From 2011 to 2017, the Sealcentre Pieterburen in The Netherlands admitted 3,775 seals for rehabilitation. Of these, 37 individuals presented clinical and radiologic signs of bone abnormalities indicative of osteomyelitis or infectious arthritis refractory to medical treatment. Seven cases resulted in euthanasia, and 30 cases underwent amputation surgery. The surgical procedure involved amputation of part of a flipper (24; two animals twice) or of a complete flipper (eight). All procedures were done under general anesthesia except one that was performed with local anesthesia, and all 30 animals were released. In two cases, the osteomyelitis presented with the rare Totenlade phenomenon, a sequestrum surrounded by new periosteal bone formation. The purpose of this retrospective study was to evaluate the outcome of the operative treatment of osteomyelitis and infectious arthritis in the flippers of harbor () and grey seals () during this 6-yr period.
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http://dx.doi.org/10.1638/2018-0221 | DOI Listing |
Int J Infect Dis
September 2025
Servicio de Brucellosis, Hospital F. J. Muñiz, 1282 Buenos Aires, Argentina.
Objectives: Brucellosis remains a significant zoonotic disease in endemic regions, with relapse and focal complications posing significant clinical challenges. This study aimed to identify risk factors associated with brucellosis relapse and focal disease in North Khorasan, Iran, over a nine-year period.
Methods: A retrospective analysis was conducted on 2,568 confirmed brucellosis cases from 2015 to 2024, using data from multiple centers.
Lancet Rheumatol
September 2025
Service de Médecine interne et polyvalente, Centre Hospitalier du Haut-Anjou, Château-Gontier, France; Université d'Angers, Inserm, CNRS, MITOVASC, Equipe MitoLab, SFR ICAT, F-49000 Angers, France. Electronic address:
Infections are increasingly recognised as a major cause of morbidity and mortality in patients with vacuoles, E1 enzyme, X-linked, autoinflammatory, somatic (VEXAS) syndrome. We conducted a systematic review to characterise the infectious burden of VEXAS syndrome and propose preventive strategies. We included 57 studies (813 patients) showing that infections in patients with VEXAS syndrome were frequent, severe in 40-60% of cases, and fatal in 6-15% of cases.
View Article and Find Full Text PDFJ Pediatric Infect Dis Soc
September 2025
Department of General Pediatrics, Pediatric Infectious Disease and Internal Medicine, Robert Debré University Hospital, Assistance Publique-Hôpitaux de Paris, Paris, France.
In a 6-year observational study of 45 children with suspected septic arthritis and no pathogen identified, early antibiotic discontinuation based on strict clinical and biological criteria was not associated with relapse during the six-month period following hospitalization, supporting this approach may be safe and reduce unnecessary antibiotic exposure.
View Article and Find Full Text PDFCureus
August 2025
Department of Rheumatology, Faculty of Medicine and Pharmacy, Ibn ROCHD University Hospital, Casablanca, MAR.
Peliosis hepatis is a rare condition characterized by dilation of the hepatic sinusoids and the presence of multiple blood-filled cystic spaces within the liver parenchyma. It has been associated with a variety of etiologies, including infectious diseases, immunological disorders, malignancy, and certain medications. We report a case of a 24-year-old male who presented with polyarthritis lasting two months.
View Article and Find Full Text PDFAnn Med
December 2025
Pediatric Orthopaedic Hospital, Honghui Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi, China.
Background: Existing classification systems for sequelae of pediatric septic arthritis of the hip (SAH) are notably complex. This study introduces a simplified radiographic classification-the Xi'an Honghui Hospital Paediatric Orthopaedic Classification (HHPO classification)-designed to enhance accuracy in treatment planning and prognostic evaluation.
Methods: A retrospective analysis was conducted involving 18 pediatric patients with SAH.