Experimental Protocols for MRI Mapping of Renal T.

Methods Mol Biol

Centre for Imaging Sciences, Division of Informatics Imaging & Data Sciences, School of Health Sciences, Faculty of Biology Medicine & Health, Manchester Academic Health Sciences Centre, University of Manchester, Manchester, UK.

Published: March 2021


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Article Abstract

The water proton longitudinal relaxation time, T, is a common and useful MR parameter in nephrology research. Here we provide three step-by-step T-mapping protocols suitable for different types of nephrology research. Firstly, we provide a single-slice 2D saturation recovery protocol suitable for studies of global pathology, where whole-kidney coverage is unnecessary. Secondly, we provide an inversion recovery type imaging protocol that may be optimized for specific kidney disease applications. Finally, we also provide imaging protocol for small animal kidney imaging in a clinical scanner.This chapter is based upon work from the COST Action PARENCHIMA, a community-driven network funded by the European Cooperation in Science and Technology (COST) program of the European Union, which aims to improve the reproducibility and standardization of renal MRI biomarkers. This analysis protocol chapter is complemented by two separate chapters describing the basic concept and experimental procedure.

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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC9703193PMC
http://dx.doi.org/10.1007/978-1-0716-0978-1_22DOI Listing

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