Category Ranking
98%
Total Visits
921
Avg Visit Duration
2 minutes
Citations
20
Article Abstract
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1016/j.amjcard.2021.01.004 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Pediatric cofactor-enhanced food anaphylaxis: A narrative review of epidemiology, pathophysiology, and clinical phenotypes.
Pediatr Allergy Immunol
September 2025
Allergy Department, Hospital Clinic, University of Barcelona, Barcelona, Spain.
Cofactors are external factors that can lower the threshold dose of an allergen and amplify the severity of allergic reactions, turning mild or moderate responses into severe anaphylaxis. These include exercise, nonsteroidal anti-inflammatory drugs (NSAIDs), alcohol, menstruation, and infections. Initially described in relation to food allergens and physical activity or NSAIDs, these reactions have been labeled under various terms, such as food-dependent exercise-induced anaphylaxis (FDEIA), wheat-dependent exercise-induced anaphylaxis (WDEIA), and food-dependent NSAID-induced anaphylaxis (FDNIA).
View Article and Find Full Text PDFAgreement between the one-minute sit-to-stand test and the six-minute walk test in assessing exercise capacity in patients with interstitial lung disease.
Monaldi Arch Chest Dis
September 2025
Department of Pulmonary, Critical Care and Sleep Medicine, All India Institute of Medical Sciences, Bhubaneswar.
The six-minute walk test (6-MWT) assesses functional exercise capacity in interstitial lung disease (ILD), providing key prognostic and functional insights. Logistical challenges, such as space and time limitations, limit its clinical use. The one-minute sit-to-stand test (1-MSTST) has emerged as a practical, space- and time-efficient alternative reflecting similar functional capacity.
View Article and Find Full Text PDFImproved AAV9-based gene therapy design for -related Leigh syndrome with minimal toxicity.
Mol Ther Methods Clin Dev
September 2025
Department of Pediatrics, UT Southwestern Medical Center, Dallas, TX 75390, USA.
Surfeit locus protein 1 (SURF1)-related Leigh syndrome is an early-onset neurodegenerative disorder characterized by a reduction in complex IV activity that disrupts mitochondrial function. Currently, there are no disease-modifying treatments available. Previously, we reported that a gene replacement therapy for -related Leigh syndrome was developed, which showed improved complex IV activity and restored exercise-induced lactate acidosis, as well as a high safety profile in wild-type (WT) mice.
View Article and Find Full Text PDFMonitoring Beta-Blocker Therapy in Adolescents with Exercise-Induced Intraventricular Gradients Using Exercise Stress Echocardiography.
Biomedicines
August 2025
Hospital Particular do Algarve, Urbanização Casal de Gambelas, Lote 2, Gambelas, 8005-226 Faro, Portugal.
Treadmill exercise stress echocardiography (ESE) is both feasible and safe in the pediatric population. Although regional wall motion abnormalities (RWMAs) have limited diagnostic utility, Doppler studies frequently demonstrate significant intraventricular pressure gradients (IVPGs) during exercise. These IVPGs, which were observed in 39% of 258 previously studied adolescents, are absent at rest.
View Article and Find Full Text PDFAssociation of exercise-induced pulmonary hypertension with nailfold capillary density in systemic sclerosis: a single-center retrospective observational study.
Arthritis Res Ther
August 2025
First Department of Internal Medicine, School of Medicine, University of Occupational and Environmental Health, Japan, 1-1 Iseigaoka, Yahata-nishi, Kitakyushu, 807-8555, Japan.
Objectives: Exercise-induced pulmonary hypertension (exercise PH) is instrumental in the early detection of pulmonary arterial hypertension. However, the prevalence and specific characteristics of exercise PH in systemic sclerosis (SSc), as well as factors that might facilitate its identification, remain inadequately understood. We investigated the clinical profiles of SSc patients diagnosed as PH, exercise PH, or non-PH.
View Article and Find Full Text PDF