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Background: Rates of alcohol use disorder (AUD) have increased in women in the last decade. Women may be more likely to engage in alcohol use to regulate stress and negative affect compared to men. Findings from our group found that life event stress was more strongly associated with new AUD in women vs. men. Our aim was to extend these findings to psychological distress, a potentially related construct to stress, using a second nationally representative dataset.
Methods: Using data from the National Survey on Drug Use and Health (NSDUH; 2008-2017, total n = 562,072), we examined time-varying associations between gender and past year serious psychological distress (SPD; Kessler-6 distress scale: scores > 13 yes, <13 no) with past year vs. absent DSM-IV AUD.
Results: A significant (p < 0.0001) gender by SPD interaction for past year vs. absent AUD demonstrated that past year SPD was associated with increased odds of past year AUD in men (OR = 3.33, 95% CI = 3.15, 3.52) and even greater odds of past year AUD in women (OR = 4.39, 95% CI = 4.14, 4.66). The gender by SPD by time interaction was not significant (p = 0.06).
Conclusions: Results highlight that while men with past year SPD were 3 times more likely to have a past year AUD, women with past year SPD were nearly 4.5 times more likely to have a past year AUD. Psychological distress is clearly an important factor in AUD in both men and women, but results suggest that other factors may be driving the increase in rates of AUD in women.
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http://dx.doi.org/10.1016/j.addbeh.2020.106815 | DOI Listing |
JAMA Netw Open
September 2025
Department of Psychiatry, Psychosomatics, and Psychotherapy, University of Lübeck, Lübeck, Germany.
Importance: Patients with inflammatory rheumatic diseases (IRDs) frequently experience psychological distress; however, access to psychological support remains limited.
Objective: To investigate the effectiveness of a digital psychological intervention for individuals with IRDs.
Design, Setting, And Participants: Participants aged 18 years or older were recruited across Germany between February 22 and June 4, 2024, if they had been diagnosed with rheumatoid arthritis, psoriatic arthritis, or systemic lupus erythematosus and reported psychological distress and reduced quality of life.
J Neurol
September 2025
Multiple Sclerosis Center, Sheba Medical Center, Derech Sheba 2, Tel Hashomer, Israel.
Introduction: Psychological stress has been proposed as a trigger for disease activity in multiple sclerosis (MS), but findings have been inconsistent. While prior research has focused largely on chronic stressors, little is known about how people with MS (pwMS) cope with acute, large-scale stress events such as war.
Objective: Examine the effects of wartime stress following the October 7, 2023 attack on disease activity in pwMS, and to assess whether emotional factors are associated with relapse risk during this period.
Int J Soc Psychiatry
September 2025
Department of Psychiatry, King George's Medical University, Lucknow, Uttar Pradesh, India.
Background: Climate distress is a psychological reaction to adverse weather events and climate change. These events can increase people's vulnerability to develop psychiatric disorders like anxiety, depression, and PTSD particularly in disaster-prone regions like India.
Aim: To explore the relationship between climate distress and psychological impact with a particular emphasis on women, elderly, and other at risk populations who owing to their health vulnerabilities, lack of resources or social roles that make them dependent on others, experience stress in the face of climate change.
Cureus
September 2025
Pediatrics, University of Nevada Reno School of Medicine, Reno, USA.
Goldenhar syndrome, a rare congenital condition, often presents with physical anomalies due to abnormal development of the first and second branchial arches, leading to facial and auricular malformations. However, the mental health challenges associated with this syndrome are often overlooked. This report describes the case of a 14-year-old Latino/Hispanic male child with Goldenhar syndrome and limited verbal communication, highlighting the complexities of managing both physical and psychological aspects of care after establishing follow-up with a pediatrician.
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September 2025
University of Calgary, Calgary, Alberta, Canada.
Objective: Psychological distress (eg, anxiety and depression) during pregnancy can disrupt fetal brain development and negatively affect infant behavior. Prenatal distress rose substantially during the COVID-19 pandemic according to most, but not all, studies, raising concerns about its potential effects on brain connectivity and behavior in infants.
Method: We investigated 63 mother-infant pairs as part of the Pregnancy during the COVID-19 Pandemic study.