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Infection
September 2025
Research Unit for Environment, Work and Health, Department of Public Health, Aarhus University, Bartholins Allé 2, Building 1260, Aarhus C, DK-8000, Denmark.
Background: Livestock-MRSA (methicillin-resistant Staphylococcus aureus) can cause infections in persons without known contact to livestock, but the route of transmission is unclear. We investigated whether the risk of livestock-MRSA infection among persons with no known contact to livestock is associated with the number of pig farms near the home, and whether this association is affected by the upwind/downwind location of the farms.
Methods: Register-based case-control study of 518 persons from Denmark with clinical infections with livestock-MRSA in 2016-2021 and no known exposure to livestock, and 4,944 matched controls.
Rheumatol Int
September 2025
Clinical Department of Rheumatology, Immunology and Internal Medicine, University Hospital in Kraków, Jakubowskiego 2, Kraków, 30-688, Poland.
Systemic lupus erythematosus (SLE) is a chronic autoimmune disease characterized by complex disturbances in both innate and adaptive immune responses, often leading to multi-organ involvement. One of the key features of SLE pathogenesis is endothelial dysfunction, which contributes to immune cell infiltration and vascular inflammation. In this context, adhesion molecules such as platelet endothelial cell adhesion molecule-1 (PECAM-1), intercellular adhesion molecule-1 (ICAM-1), and vascular cell adhesion molecule-1 (VCAM-1) may reflect the degree of endothelial activation.
View Article and Find Full Text PDFInt J Cancer
September 2025
Faculty of Dental Medicine and Oral Health Sciences, McGill University, Montreal, Quebec, Canada.
In Canada, the incidence of human papillomavirus (HPV)-related head and neck cancer (HNC) is increasing. The role of multiple oral HPV infections in HNC etiology remains unclear, and evidence of HPV vaccination's effectiveness in reducing HNC incidence is limited. We investigated oral HPV co-infection patterns, estimated the association between multiple oral HPV infections and HNC risk, and the effect of eliminating vaccine-targeted HPV genotypes on HNC incidence.
View Article and Find Full Text PDFJ Am Coll Surg
September 2025
Division of Trauma/Surgical Critical Care, University of Tennessee Health Science Center, Memphis, Tennessee.
Background: Gastrointestinal bleeding (GiB) is associated with hypoperfusion, cytokine release, and alterations to the mucosal barrier frequently seen in the critical care population. Risk factors in the population at large have been well-studied, but few have specifically addressed the unique circumstances surrounding critically ill trauma patients. We aimed to evaluate the incidence and risk factors for GiB in the trauma critical care population.
View Article and Find Full Text PDFAnn Afr Med
August 2025
Department of General Medicine, Dr. D. Y. Patil Medical College, Hospital and Research Centre, Pune, Maharashtra, India.
Background: Prediabetes represents a transitional state in glucose metabolism with an increasing global and national prevalence, particularly in India. Recent evidence suggests that both thyroid dysfunction and chronic low-grade inflammation may play pivotal roles in the progression of prediabetes to overt Type 2 diabetes mellitus (T2DM). Thyroid hormones regulate glucose metabolism, while inflammatory markers such as white blood cell (WBC) count and high-sensitivity C-reactive protein (hs-CRP) are indicators of systemic inflammation often elevated in metabolic disorders.
View Article and Find Full Text PDF