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http://dx.doi.org/10.21037/qims-20-628 | DOI Listing |
Zhonghua Jie He He Hu Xi Za Zhi
September 2025
Department of Allergy, Beijing Key Laboratory of Precision Medicine for Diagnosis and Treatment on Allergic Diseases, National Clinical Research Center for Dermatologic and Immunologic Diseases, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College
Inhaled and intranasal corticosteroids are widely used in the management of allergic respiratory diseases. Delayed drug hypersensitivity reactions to budesonide are a rare adverse drug reaction characterized by non-immunoglobulin E (IgE)-mediated clinical manifestations, including localized or systemic contact dermatitis, mucosal edema, and paradoxical worsening of pre-existing symptoms. However, such reactions are often underdiagnosed due to atypical presentations.
View Article and Find Full Text PDFOphthalmic Plast Reconstr Surg
September 2025
Department of Ophthalmology, Oculoplastic and Orbital Surgery, Hospital Universitario Austral, Pilar, Argentina.
This article presents the rare occurrence of a trichilemmal cyst in the orbit of a 69-year-old female patient, who presented with a headache of acute onset and relative unilateral proptosis of the left eye. CT scan showed a cystic, well-demarcated, round hypodense lesion, with spotted calcification. Surgery was performed for the extraction and analysis of the lesion, which showed typical histological findings of a trichilemmal tumor.
View Article and Find Full Text PDFInt J Surg Case Rep
September 2025
Department of Otorhinolaryngology, Al Mouwasat University Hospital, Damascus University, Damascus, Syria; Faculty of Medicine, Damascus University, Damascus, Syria.
Introduction: Antrochoanal polyps (ACPs) typically extend posteriorly into the choana and nasopharynx; orbital invasion is exceptionally rare. This report details an atypical ACP with orbital extension in a coagulopathic patient, highlighting diagnostic and surgical complexities.
Case Presentation: A 46-year-old woman with severe Factor V deficiency (0.
Hematol Transfus Cell Ther
September 2025
Department of Medicine, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Verspeeten Family Cancer Centre, London Health Sciences Centre, London, ON, Canada; Department of Oncology, Schulich School of Medicine and Dentistry, Western University, London, ON, Canada; Th
Background: Hemophagocytic lymphohistiocytosis (HLH) is a life-threatening immune disorder characterized by excessive inflammation and multiorgan involvement. Rarely, HLH can manifest with signs and symptoms isolated to the central nervous system (CNS). This case report highlights the unique clinical course of CNS-isolated HLH in a 19-year-old female who, despite a nine-year delay in diagnosis, achieved disease remission following a hematopoietic stem cell transplant (HSCT).
View Article and Find Full Text PDFOcular relapse in pediatric acute lymphoblastic leukemia (ALL) is rare and typically associated with central nervous system or bone marrow involvement. Anterior segment infiltration as the sole manifestation of relapse is exceptionally uncommon and may mimic noninfectious uveitis, leading to diagnostic delay. We report the case of a 4-year-old boy with a history of B-cell precursor ALL, diagnosed at age 2 and treated according to the ALL IC BFM 2009 protocol.
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